OCT in Alzheimer's disease: thinning of the RNFL and superior hemiretina.

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Abstract

Peripapillary retinal nerve fiber layer (pRNFL) and internal macular layer thinning have been demonstrated in Alzheimer's disease (AD) with optical coherence tomography (OCT) studies. The purpose of this study is to compare the pRNFL thickness and overall retinal thickness (RT) in AD patients with non-AD patients, using spectral domain optical coherence tomography (SD-OCT) and determine the sectors most characteristically affected in AD.

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Journal

Journal ID (iso-abbrev): Graefes Arch. Clin. Exp. Ophthalmol.

Title: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

Publisher: Springer Nature

ISSN (Electronic): 1435-702X

ISSN (Print): 0721-832X

Publication date (Electronic): Jun 22 2017

Affiliations

[1 ] Department of Ophthalmology, Central Lisbon Hospital Center, Lisbon, Portugal. cunha.oft@gmail.com.

[2 ] NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal. cunha.oft@gmail.com.

[3 ] Department of Neuro-Ophthalmology, Central Lisbon Hospital Center, 1169-050, Lisboa, Portugal. cunha.oft@gmail.com.

[4 ] Department of Ophthalmology, Central Lisbon Hospital Center, Lisbon, Portugal.

[5 ] Department of Neurology, Central Lisbon Hospital Center, Lisbon, Portugal.

[6 ] Epidemiology and Statistics Unit, Research Centre, Central Lisbon Hospital Center, Lisbon, Portugal.

[7 ] NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal.

[8 ] CEAUL (Center of Statistics and Applications), Lisbon University, Lisbon, Portugal.

[9 ] Visual Sciences Study Center, Faculty of Medicine, Lisbon University, Lisbon, Portugal.

Article

Publisher Item ID: 10.1007/s00417-017-3715-9

DOI: 10.1007/s00417-017-3715-9

PubMed ID: 28643042

SO-VID: 116f4ad8-8e29-46e3-8c6c-975a3cee6ee1

History

Keywords: Macula,Spectral domain optical coherence tomography,Retina,Alzheimer’s disease,RNFL

Data availability:

Keywords: Macula, Spectral domain optical coherence tomography, Retina, Alzheimer’s disease, RNFL

OCT in Alzheimer's disease: thinning of the RNFL and superior hemiretina.

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Alternative approaches to Alzheimer's Disease

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