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      Ventajas de la quimioterapia domiciliaria en los enfermos adultos con neoplasias: revisión sistemática Translated title: Home chemotherapy advantages in adult neoplasia sufferers: a systematic review

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          Abstract

          Resumen Objetivo: Conocer la evidencia científica con respecto a las posibles ventajas que ofrece la quimioterapia domiciliaria a los enfermos adultos con neoplasias. Método: Revisión crítica y sistemática. Los datos se obtuvieron de la consulta a las siguientes bases de datos bibliográficas: MEDLINE (vía PubMed), Cochrane Library, Embase, Scopus y Web of Science. Los términos utilizados, como descriptores y como texto en los campos de registro del título y el resumen, fueron “Home Care Services”, “Drug Therapy” y “Neoplasms”, utilizando los filtros «Humans», «Adult: 19+ years» y «Clinical Trial». Fecha de la búsqueda octubre de 2019. La calidad documental de los artículos se evaluó mediante el cuestionario CONSORT. Resultados: De las 790 referencias recuperadas, tras depurar las repeticiones y aplicar los criterios de inclusión y exclusión, se seleccionaron 15 ensayos clínicos. En 12 (80%) de los ensayos revisados se observó que la quimioterapia administrada en el hogar fue segura, factible, beneficiosa y predominantemente preferida por los pacientes. Con respecto al coste del tratamiento se comprobó discrepancias entre algunos trabajos, donde 3 (20%) estudios señalaban un mayor coste del tratamiento domiciliario. Conclusiones: La quimioterapia domiciliaria es una alternativa factible y segura para los pacientes, la cual es preferida por estos y sus cuidadores. El mayor o menor coste dependió principalmente del medicamento y tipo de tratamiento.

          Translated abstract

          Abstract Objective: To know the scientific evidence regarding the possible advantages offered by home chemotherapy to adult sufferers with neoplasia. Method: Critical and systematic review. Data were obtained from the query of the following database: MEDLINE (via PubMed), Cochrane Library, Embase, Scopus and Web of Science. Terms used as descriptors and as text in the title and summary record fields were: “Home Care Services”, “Drug Therapy” and “Neoplasms”, using the filters «Humans», «Adult: 19+ years» and «Clinical Trial». Searching date October 2019. The documental quality of the articles was evaluated by using CONSORT questionnaire. Results: From 790 recovered references, after refining the repetitions and applying the inclusion and exclusion criteria, 15 clinical trials were selected. In 12 (80%) of the revised trials it was observed that chemotherapy administrated at home was safe, feasible, beneficial and predominantly preferred by the patients. Regarding the cost of treatment, discrepancies were found between some trials, where 3 studies (20%) indicated a higher cost of home treatment. Conclusions: Home chemotherapy is a feasible and safe alternative for patients, which is preferred by them and their caregivers. The higher or lower cost depended mainly on the medication and type of treatment.

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          Most cited references34

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          CONSORT 2010 statement: extension checklist for reporting within person randomised trials

          Evidence shows that the quality of reporting of randomised controlled trials (RCTs) is not optimal. The lack of transparent reporting impedes readers from judging the reliability and validity of trial findings and researchers from extracting information for systematic reviews and results in research waste. The Consolidated Standards of Reporting Trials (CONSORT) statement was developed to improve the reporting of RCTs. Within person trials are used for conditions that can affect two or more body sites, and are a useful and efficient tool because the comparisons between interventions are within people. Such trials are most commonly conducted in ophthalmology, dentistry, and dermatology. The reporting of within person trials has, however, been variable and incomplete, hindering their use in clinical decision making and by future researchers. This document presents the CONSORT extension to within person trials. It aims to facilitate the reporting of these trials. It extends 16 items of the CONSORT 2010 checklist and introduces a modified flowchart and baseline table to enhance transparency. Examples of good reporting and evidence based rationale for CONSORT within person checklist items are provided.
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            A meta-analysis of "hospital in the home".

            To assess the effect of "hospital in the home" (HITH) services that significantly substitute for inhospital time on mortality, readmission rates, patient and carer satisfaction, and costs.
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              Systematic reviews in nutrition: standardized methodology.

              The objective of this study is to establish a methodological proposal in order to carry out qualitative systematic reviews and apply these findings to a review of Omega-3 Fatty Acids with respect to health and illness. Based on a methodological proposal, a general protocol was developed to provide a sound basis for the preparation of the reviews in this journal supplement. A systematic technique was proposed in order to revise the existing scientific literature on Omega-3 Fatty Acids, with particular emphasis on aspects relating to health and illness. The aim of qualitative systematic reviews is to collate and summarise the results of the primary studies reviewed which will be carried out through a descriptive synthesis. It can be concluded that systematic reviews provide a summary of the existing primary documents on a specific scientific question. The detailed and explicit methods used lead to the identification, critical evaluation and synthesis of the scientific literature. Furthermore, both bias and random effects are reduced, resulting in more reliable data from which to draw conclusions and make recommendations to support decision-making.
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                Author and article information

                Journal
                had
                Hospital a Domicilio
                Hosp. domic.
                Centro Internacional Virtual de Investigación en Nutrición (CIVIN) (Alicante, Alicante, Spain )
                2530-5115
                March 2020
                : 4
                : 1
                : 25-41
                Affiliations
                [1] Valencia orgnameUniversidad Miguel Hernández de Elche orgdiv1Campus de Sant Joan d'Alacant orgdiv2Facultad de Farmacia Spain
                [2] Valencia orgnameUniversidad Miguel Hernández de Elche orgdiv1Campus de Sant Joan d'Alacant orgdiv2Departamento de Salud Pública e Historia de la Ciencia Spain
                Article
                S2530-51152020000100004 S2530-5115(20)00400100004
                10.22585/hospdomic.v4i1.98
                11a954f7-af09-4a83-9fcb-e40ad58063fb

                This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

                History
                : 13 January 2020
                : 15 January 2020
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 34, Pages: 17
                Product

                SciELO Spain

                Categories
                Artículos de revisión

                Drug Therapy,Home Care Services, Hospital-Based,Antineoplastic Agents,Satisfacción del Paciente,Cytostatic Agents,Treatment Adherence and Compliance,Home Care Services,Citostáticos,Patient Satisfaction,Quimioterapia,Servicios de Atención a Domicilio Provisto por Hospital,Antineoplásicos,Servicios de Atención de Salud a Domicilio,Cumplimiento y Adherencia al Tratamiento

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