This study aimed to assess the validity and reliability of the Malay version Boston Carpal Tunnel Questionnaire (M-BCTQ). A cross-sectional study was used to generate the final version of M-BCTQ that was administered to 55 patients for psychometric testing. M-BCTQ had excellent test-retest reliability with ICCs value 0.837 for Symptom Severity Scale (SSS) and 0.913 for Functional Status Scale (FSS). The Cronbach alpha coefficient for the internal consistencies was reported at 0.864 for SSS and 0.893 for the FSS. A strong correlation was found with the Malay version of Disability of Arm, Shoulder and Hand Questionnaire (MV-DASH) as Spearman correlation for construct validity was 0.791 for SSS and 0.831 for FSS.