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      Translation, and interobserver and test–retest reliability of the Brazilian Portuguese version of Children's Hospital Oakland Hip Evaluation Scale for patients with sickle cell disease

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          Abstract

          Background

          The Children's Hospital Oakland Hip Evaluation Scale is a disease-specific tool for the clinical and functional assessment of the hip in sickle cell disease.

          Objectives

          To translate the tool into Brazilian Portuguese and evaluate the interobserver and test–retest reliability.

          Methods

          Eighteen patients diagnosed with sickle cell disease and a mean age of 49 ± 11.9 years participated in the study. The scale was applied by two evaluators who did not speak to each other regarding their understanding of the tool and who had no prior training. Interobserver and test–retest reliability of individual items and of the total score were evaluated using the intraclass correlation coefficient and the Bland–Altman method.

          Results

          When the overall score for each hip was considered, the test–retest intraclass correlation coefficient score for the right hip was 0.95 (0.89–0.98) and for the left hip it was 0.96 (0.91–0.98). Considering all assignments (total score), the score was 0.96 (0.90–0.98). The test–retest intraclass correlation coefficient varied from 0.76 to 1 for 18 of the 27 items (excellent) and from 0.53 to 0.75 for nine items (moderate). When the overall score for each hip was considered, the interobserver intraclass correlation coefficient for both hips was 0.94 (0.86–0.98). Considering all assignments, the total score was 0.94 (0.86–0.98). The interobserver intraclass correlation coefficient varied from 0.48 to 0.75 for 18 out of 27 items (moderate) and varied from 0.77 to 1 for the remaining nine items (excellent).

          Conclusion

          The results demonstrate that the Brazilian version of the Children's Hospital Oakland Hip Evaluation Scale presented adequate interobserver and test–retest reliability and that the version can be used to evaluate clinical function in sickle cell disease patients, producing consistent, standardized and reproducible results.

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          Most cited references24

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          Relação entre intensidade de dor e capacidade funcional em indivíduos obesos com osteoartrite de joelho

          CONTEXTUALIZAÇÃO: A osteoartrite (OA) de joelho é uma doença crônica que acomete a cartilagem articular, provocando alterações ósseas, dor e rigidez à movimentação. A obesidade é um dos seus principais fatores de risco. As queixas de dificuldades funcionais são freqüentes, especialmente para a locomoção, que se torna mais lenta. Com os crescentes níveis de obesidade no Brasil, torna-se importante compreender como a OA de joelho afeta a capacidade funcional humana, a fim de se elaborar medidas de tratamento e prevenção. OBJETIVO: Analisar a influência da intensidade de dor, gravidade radiográfica, grau de obesidade e duração dos sintomas na capacidade funcional de indivíduos obesos com OA de joelho. MÉTODO: A intensidade de dor foi medida pelo questionário Western Ontario and McMaster Universities Index (WOMAC) e durante os testes funcionais. A gravidade radiográfica foi analisada pela classificação Kellgren-Lawrence e o grau de obesidade pelo índice de massa corporal (IMC). Foram realizados quatro testes funcionais de velocidade: marcha usual e rápida, subir e descer escadas. RESULTADOS: A amostra foi constituída de 31 mulheres e 4 homens, com idade média de 51,65 ± 10,72 anos e IMC médio de 41,16 ± 8,37 kg/m². As atividades em escadas estavam associadas a níveis mais intensos de dor. Apenas a intensidade de dor apresentou correlações significativas com os resultados nos testes de velocidade. CONCLUSÃO: A intensidade de dor é um fator que influencia a realização de atividades funcionais em indivíduos obesos com OA de joelho, mas outros estudos são necessários para identificar os fatores determinantes de capacidade funcional nesta população.
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            Reliability of inclinometer and goniometric measurements of hip extension flexibility using the modified Thomas test.

            Our objectives were to examine interrater reliability for inclinometer and goniometric measurements of hip extension flexibility and the intra- and interrater reliability between instruments when measuring hip extension flexibility with the modified Thomas test. The modified Thomas test is frequently used by clinicians to assess hip extension flexibility. Studies examining the reliability of measures of the modified Thomas test are limited. This study included 42 healthy subjects. The modified Thomas test was performed on each subject to quantify hip extension flexibility by using an inclinometer and a goniometer. High interrater reliability was determined for each instrument (r = 0.91-0.93; ICC = 0.89-0.92). High intrarater parallel-forms reliability was found for each examiner between the instruments (r = 0.089-0.92; ICC = 0.91-0.93). High interrater parallel-forms reliability also was found between instruments (r = 0.86-0.93; ICC = 0.86-0.92). The high correlations obtained in this study suggest that the inclinometer and the goniometer are reliable instruments for measuring hip extension flexibility. The results also indicate that the two instruments can be used interchangeably for measuring hip extension flexibility.
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              Sickle cell disease and nitric oxide: a paradigm shift?

              Traditionally the pathophysiology of sickle cell disease is thought to result from the polymerization of hemoglobin S in red cells, under hypoxic conditions, resulting in the occlusion of blood vessels. Adhesion of cells to the venular endothelium also appears to play a role. Recent studies have also suggested that in addition to the polymerization of hemoglobin S in the red blood cell, a deficiency of the endogenous vasodilator, nitric oxide may be involved. Hemoglobin released as a result of hemolysis rapidly consumes nitric oxide resulting in a whole program of events that inhibit blood flow. Therapies directed at decreasing the destruction of nitric oxide, increasing the production of nitric oxide, or amplifying the nitric oxide response may prove beneficial.
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                Author and article information

                Contributors
                Journal
                Hematol Transfus Cell Ther
                Hematol Transfus Cell Ther
                Hematology, Transfusion and Cell Therapy
                Sociedade Brasileira de Hematologia e Hemoterapia
                2531-1379
                2531-1387
                24 March 2018
                Jul-Sep 2018
                24 March 2018
                : 40
                : 3
                : 226-232
                Affiliations
                [a ]Centro Universitário Nossa Senhora do Patrocínio (CEUNSP), Itu, SP, Brazil
                [b ]Universidade Federal de São Carlos (UFSCAR), São Carlos, SP, Brazil
                [c ]Universidade Estadual de Campinas (UNICAMP), Campinas, SP, Brazil
                Author notes
                [* ] Corresponding author at: Hematology and Blood Transfusion Center, Universidade Estadual de Campinas (UNICAMP), Rua Carlos Chagas, 480, CEP 13083-878, Campinas, SP, Brazil. czanoni@ 123456fcm.unicamp.br
                Article
                S2531-1379(18)30054-3
                10.1016/j.htct.2018.01.006
                6738485
                31787155
                1240f4cb-8d8f-42a3-a9b0-84fa8b7374a3
                © 2018 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier Editora Ltda.

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 31 August 2016
                : 24 January 2018
                Categories
                Original Article

                translation,sickle cell disease,scales,hip,physiotherapy
                translation, sickle cell disease, scales, hip, physiotherapy

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