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      Concurrent chemoimmunotherapy in metastatic clear cell sarcoma: a case report.

      Tumori

      Leg, Antineoplastic Combined Chemotherapy Protocols, therapeutic use, Cyclophosphamide, administration & dosage, Dacarbazine, Disease Progression, Epirubicin, Fatal Outcome, Humans, Immunotherapy, methods, Interferon-alpha, Lung Neoplasms, complications, drug therapy, secondary, therapy, Male, Middle Aged, Pleural Effusion, Malignant, etiology, Recombinant Proteins, Sarcoma, Clear Cell, pathology, Treatment Outcome, Vincristine

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          Abstract

          Clear cell sarcoma is a rare tumor with a poor prognosis. The therapeutic approach in the metastatic disease stage is controversial: to the authors' knowledge the use of concurrent chemoimmunotherapy has not been previously reported. We present a case of a 57-year-old male with metastatic clear cell sarcoma treated simultaneously with subcutaneous interferon-a 2b and six courses of chemotherapy according to the CyVEDIC regimen. Disease stabilization lasting 17 months was achieved.

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          10774576

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