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      Burden of Cardiovascular Disease among Multi-Racial and Ethnic Populations in the United States: an Update from the National Health Interview Surveys

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          Abstract

          Purpose: The study aimed to provide new evidence of health disparities in cardiovascular disease (CVD) and diabetes mellitus (DM), and to examine their associations with lifestyle-related risk factors across the U.S. multi-racial and ethnic groups.

          Methods: The analysis included a randomized population sample of 68,321 subjects aged ≥18 years old who participated in the U.S. 2012 and 2013 National Health Interview Surveys. Hypertension, coronary heart disease (CHD), stroke, and DM were classified according to participants’ self-report of physician diagnosis. Assessments of risk factors were measured using standard survey instruments. Associations of risk factors with hypertension, CHD, stroke, and DM were analyzed using univariable and multivariable analysis methods.

          Results: Non-Hispanic (NH)-Blacks had significantly higher odds of hypertension, while Hispanics had significantly lower odds of hypertension, and NH-Asians and Hispanics had significantly lower odds of stroke than NH-Whites ( p < 0.001). All minority groups, NH-Blacks, NH-Asians, and Hispanics had significantly higher odds of DM, but they had significantly lower odds of CHD than NH-Whites ( p < 0.001). Increased body weight, cigarette smoking, and physical inactivity were significantly associated with increased odds of hypertension, CHD, stroke, and DM ( p < 0.001). However, the strengths of associations between lifestyle-related factors and the study outcomes were different across racial and ethnic groups. NH-Asians with BMI ≥30 kg/m 2 had the highest odds ratios (OR, 95% CI) for hypertension (5.37, 4.01–7.18), CHD (2.93, 1.90–4.52), and stroke (2.23, 1.08–4.61), and had the second highest odd ratios for DM (3.78, 2.68–5.35) than NH-Whites, NH-Blacks, and Hispanics.

          Conclusion: CVD and DM disproportionately affect the U.S. multi-racial and ethnic population. Although lifestyle-related risk factors are significantly associated with increased odds of CVD and DM, the magnitudes of these associations are different by race and ethnicity.

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          Most cited references13

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          Heart disease and stroke statistics--2014 update: a report from the American Heart Association.

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            Self-report and medical record report agreement of selected medical conditions in the elderly.

            This study assessed agreement between self- and medical record report of medical conditions in an elderly population. Medical charts of 120 participants in a screening program were abstracted, and the questionnaire report of eight major conditions was compared with the medical record. There was substantial or moderate agreement between self-report and medical record report for each condition, although strength of agreement varied by condition. Self-report by elderly individuals compares favorably with medical record report of medical conditions.
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              Can self-reported strokes be used to study stroke incidence and risk factors?: evidence from the health and retirement study.

              Most stroke incidence studies use geographically localized (community) samples with few national data sources available. Such samples preclude research on contextual risk factors, but national samples frequently collect only self-reported stroke. We examine whether incidence estimates from clinically verified studies are consistent with estimates from a nationally representative US sample assessing self-reported stroke. Health and Retirement Study (HRS) participants (n=17 056) age 50+ years were followed for self- or proxy-reported first stroke (1293 events) from 1998 to 2006 (average, 6.8 years). We compared incidence rates by race, sex, and age strata with those previously documented in leading geographically localized studies with medically verified stroke. We also examined whether cardiovascular risk factor effect estimates in HRS are comparable to those reported in studies with clinically verified strokes. The weighted first-stroke incidence rate was 10.0 events/1000 person-years. Total age-stratified incidence rates in whites were mostly comparable with those reported elsewhere and were not systematically higher or lower. However, among blacks in HRS, incidence rates generally appeared higher than those previously reported. HRS estimates were most comparable with those reported in the Cardiovascular Health Study. Incidence rates approximately doubled per decade of age and were higher in men and blacks. After demographic adjustment, all risk factors predicted stroke incidence in whites. Smoking, hypertension, diabetes, and heart disease predicted incident stroke in blacks. Associations between known risk factors and stroke incidence were verified in HRS, suggesting that misreporting is nonsystematic. HRS may provide valuable data for stroke surveillance and examination of classical and contextual risk factors.
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                Author and article information

                Contributors
                Journal
                Front Cardiovasc Med
                Front Cardiovasc Med
                Front. Cardiovasc. Med.
                Frontiers in Cardiovascular Medicine
                Frontiers Media S.A.
                2297-055X
                10 November 2014
                2014
                : 1
                : 8
                Affiliations
                [1] 1Department of Epidemiology and Biostatistics, School of Public Health, Drexel University , Philadelphia, PA, USA
                [2] 2Department of Environmental and Occupational Health, School of Public Health, Drexel University , Philadelphia, PA, USA
                [3] 3Department of Medicine, Drexel University College of Medicine , Philadelphia, PA, USA
                [4] 4College of Computing and Informatics, Drexel University , Philadelphia, PA, USA
                [5] 5Department of Cardiology, First Affiliated Hospital of Chongqing Medical University , Chongqing, China
                [6] 6National Center for Chronic and Non-Communicable Disease Control and Prevention, Centers for Disease Control and Prevention , Beijing, China
                [7] 7Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford , Oxford, UK
                Author notes

                Edited by: Renate B. Schnabel, University Heart Center Hamburg, Germany

                Reviewed by: Leonardo Roever, University of São Paulo, Brazil; Federal University of Uberlândia, Brazil; Emmi Tikkanen, University of Helsinki, Finland

                *Correspondence: Longjian Liu, Department of Epidemiology and Biostatistics, Drexel University School of Public Health, 3215 Market ST, Philadelphia, PA 19104, USA e-mail: longjian.liu@ 123456Drexel.edu

                This article was submitted to Cardiovascular Epidemiology, a section of the journal Frontiers in Cardiovascular Medicine.

                Article
                10.3389/fcvm.2014.00008
                4668845
                26664859
                12caf022-6217-47f0-acb5-c9c3b4aeb98a
                Copyright © 2014 Liu, Núṅez, An, Liu, Chen, Ma, Chou, Chen and Eisen.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 31 August 2014
                : 23 October 2014
                Page count
                Figures: 1, Tables: 5, Equations: 0, References: 15, Pages: 8, Words: 5686
                Categories
                Cardiovascular Medicine
                Original Research

                cardiovascular disease,risk factors,multi-race and ethnicity,usa

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