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      A beginner’s guide to getting involved in science advocacy

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          Abstract

          Every scientist in the United States likely has a story of how the federal funding crisis for biomedical research has affected him or her personally. The sharing of these powerful anecdotes will enable policy makers to fully grasp the extent to which the decline in federal funding has negatively affected the scientific community. However, many scientists do not know where to begin or are uncertain that their advocacy efforts will have an impact. In an effort to encourage more scientists to become involved in science advocacy, we describe how to form and maintain a student science advocacy group.

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          Most cited references3

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          Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder.

          Increasing evidence indicates that metabolic disorders in offspring can result from the father's diet, but the mechanism remains unclear. In a paternal mouse model given a high-fat diet (HFD), we showed that a subset of sperm transfer RNA-derived small RNAs (tsRNAs), mainly from 5' transfer RNA halves and ranging in size from 30 to 34 nucleotides, exhibited changes in expression profiles and RNA modifications. Injection of sperm tsRNA fractions from HFD males into normal zygotes generated metabolic disorders in the F1 offspring and altered gene expression of metabolic pathways in early embryos and islets of F1 offspring, which was unrelated to DNA methylation at CpG-enriched regions. Hence, sperm tsRNAs represent a paternal epigenetic factor that may mediate intergenerational inheritance of diet-induced metabolic disorders.
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            The Good Words—Science Tweeters You May Not Know about but Should

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              Write (with a Pen!) in the Fight for Science Funding

              V. A. York (2014)
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                Author and article information

                Contributors
                Role: Monitoring Editor
                Journal
                Mol Biol Cell
                Mol. Biol. Cell
                molbiolcell
                mbc
                Mol. Bio. Cell
                Molecular Biology of the Cell
                The American Society for Cell Biology
                1059-1524
                1939-4586
                15 April 2016
                : 27
                : 8
                : 1181-1184
                Affiliations
                [1]Graduate Division of Biological and Biomedical Sciences and Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322
                University of Virginia
                Author notes

                These are co–first authors.

                *Address correspondence to: Amanda L. York ( alyork@ 123456emory.edu ).
                Article
                E16-01-0016
                10.1091/mbc.E16-01-0016
                4831871
                27079651
                12ef6682-5adb-454f-b41a-94d3e0501f24
                © 2016 Ruppersburg and York. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License ( http://creativecommons.org/licenses/by-nc-sa/3.0).

                “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

                History
                : 12 January 2016
                : 18 February 2016
                : 23 February 2016
                Categories
                Perspectives

                Molecular biology
                Molecular biology

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