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Abstract
Research in hemodialysis adaptation has been facilitated by the use of reliable outcome
measures such as BUN, K, and interdialysis weight gain. Their use, however, has at
times been impressionistic, without reference to the actual range and distribution
of those markers in a large population of dialysis patients over a long period of
time. This study is a retrospective review to determine that range and distribution
at one center. We found the interdialysis weight gains for most patients to be much
higher than the levels used in the literature as cut-off points in determining 'non-compliance'.
High levels on non-compliance in previous reports may be inflated. Significant correlations
among the three biological markers and between each marker and staff assessment of
compliance validate the use of inter-dialysis weight gain. Suggestions are made for
interpreting such data in the future.