11
views
0
recommends
+1 Recommend
2 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Theileria, Babesia, and Anaplasma detected by PCR in ruminant herds at Bié Province, Angola Translated title: Theileria, Babesia, et Anaplasma detectés par PCR dans des troupeaux de ruminants de la Province de Bié en Angola

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Distribution of Anaplasma spp., Babesia spp., Theileria spp., and Ehrlichia ruminantium, was for the first time studied in Bié Province, central Angola. We examined 76 blood samples of cattle originated from seven farms, and 13 blood samples of goats from two farms employing molecular genetic tools (PCR). Most prevalent was A. ovis-infection in goats (100%) and A. marginale-infection in cattle (38% of examined animals, and six out of seven farms). B. bigemina-infection was detected in only one specimen at Andulo, whereas B. bovis was not detected in Bié. We did not detected T. parva, the causative agent of serious diseases in cattle; nevertheless, infection by T. velifera was quite frequent (14% of examined animals, and five out of seven farms). Causative agent of heartwater disease – E. ruminantium, was not detected. Taking into account short-term perspective of PCR methods in monitoring of epidemiological status in herds, the number of infected animals and distribution of detected pathogens should not be ignored.

          Translated abstract

          La distribution d’ Anaplasma spp., Babesia spp., Theileria spp. et Ehrlichia ruminantium a été pour la première fois étudiée dans la province de Bié, au centre de l’Angola. Nous avons examiné par PCR 76 échantillons de sang de bétail provenant de sept fermes et 13 échantillons de sang de chèvres de deux fermes. L’infection par A. ovis a été observée chez 100 % des chèvres, celle par A. marginale chez 38 % des animaux du bétail de six fermes sur sept, celle par B. bigemina chez seulement un spécimen à Andulo, tandis que B. bovis n’a pas été détecté dans cette province. Nous n’avons pas détecté T. parva, l’agent causal de maladies graves du bétail; néanmoins, l’infection par T. velifera était assez fréquente (14 % d’animaux examinés de cinq fermes sur sept). E. ruminantium n’a pas été détecté. Le recours à la PCR pour le suivi du statut épidémiologique des troupeaux (nombre d’animaux infectés et distribution des agents pathogènes) ne devrait pas être ignoré à court terme.

          Related collections

          Most cited references 25

          • Record: found
          • Abstract: found
          • Article: not found

          The natural history of Anaplasma marginale.

          The intracellular pathogen Anaplasma marginale (Rickettsiales: Anaplasmataceae), described by Sir Arnold Theiler in 1910, is endemic worldwide in tropical and subtropical areas. Infection of cattle with A. marginale causes bovine anaplasmosis, a mild to severe hemolytic disease that results in considerable economic loss to both dairy and beef industries. Transmission of A. marginale to cattle occurs biologically by ticks and mechanically by biting flies and by blood-contaminated fomites. Both male ticks and cattle hosts become persistently infected with A. marginale and serve as reservoirs of infection. While erythrocytes are the major site of infection in cattle, A. marginale undergoes a complex developmental cycle in ticks that begins by infection of gut cells, and transmission to susceptible hosts occurs from salivary glands during feeding. Major surface proteins (MSPs) play a crucial role in the interaction of A. marginale with host cells, and include adhesion proteins and MSPs from multigene families that undergo antigenic change and selection in cattle, thus contributing to maintenance of persistent infections. Many geographic strains of A. marginale have been identified worldwide, which vary in genotype, antigenic composition, morphology and infectivity for ticks. Isolates of A. marginale may be maintained by independent transmission events and a mechanism of infection/exclusion in cattle and ticks. The increasing numbers of A. marginale genotypes identified in some geographic regions most likely resulted from intensive cattle movement. However, concurrent A. marginale strain infections in cattle was reported, but these strains were more distantly related. Phylogenetic studies of selected geographic isolates of A. marginale, using msp4 and msp1alpha, provided information about the biogeography and evolution of A. marginale, and msp1alpha genotypes appear to have evolved under positive selection pressure. Live and killed vaccines have been used for control of anaplasmosis and both types of vaccines have advantages and disadvantages. Vaccines have effectively prevented clinical anaplasmosis in cattle but have failed to block A. marginale infection. Vaccines are needed that can prevent clinical disease and, simultaneously, prevent infection in cattle and ticks, thus eliminating these hosts as reservoirs of infection. Advances in genomics, proteomics, immunology and biochemical and molecular technologies during the last decade have been applied to research on A. marginale and related organisms, and the recent development of a cell culture system for A. marginale has provided a format for studying the pathogen/tick interface. Recent advancements and new research methodologies should provide additional opportunities for development of new strategies for control and prevention of bovine anaplasmosis.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            International collaborative research: significance of tick-borne hemoparasitic diseases to world animal health.

            A general review is given of the tick-borne hemoparasitic diseases of greatest economic importance in ruminants, babesiosis, anaplasmosis, theileriosis and cowdriosis, each caused by one or more species of hemoparasites. Most affected are cattle and small ruminants, buffalo are more resistant and little is known regarding camels. The situation varies from one continent or region to another. Innate and breed susceptibility to these diseases are of tremendous importance. Disease in the field cannot be considered separated from the whole complex of tick-borne diseases and from the ticks themselves, particularly if the aim is to attain endemic stability. International coordination is needed now that research funds are scarce. An appendix contains tables with hemoparasites of various domestic animals and notes with background details.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Babesiosis of cattle.

              Tick fever or cattle fever (babesiosis) is economically the most important arthropod-borne disease of cattle worldwide with vast areas of Australia, Africa, South and Central America and the United States continuously under threat. Tick fever was the first disease for which transmission by an arthropod to a mammal was implicated at the turn of the twentieth century and is the first disease to be eradicated from a continent (North America). This review describes the biology of Babesia spp. in the host and the tick, the scale of the problem to the cattle industry, the various components of control programmes, epidemiology, pathogenesis, immunity, vaccination and future research. The emphasis is on Babesia bovis and Babesia bigemina.
                Bookmark

                Author and article information

                Journal
                Parasite
                Parasite
                parasite
                Parasite
                EDP Sciences
                1252-607X
                1776-1042
                November 2012
                15 November 2012
                : 19
                : 4 ( publisher-idID: parasite/2012/04 )
                : 417-422
                Affiliations
                [1 ] Department of Biology and Wildlife Diseases, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno Palackého 1-3 612 42 Brno Czech Republic
                [2 ] Department of Sustainable Technologies, Institute of Tropics and Subtropics, Czech University of Life Sciences Prague Kamýcká 129 165 21 Praha 6 Czech Republic
                [3 ] CEITEC-Central European Institute of Technology, University of Veterinary and Pharmaceutical Sciences Brno Palackého 1-3 612 42 Brno Czech Republic
                Author notes
                [* ]Correspondence: Pavel Široký. Tel.: +420 541 562 635 - Fax: +420 541 562 631. E-mail: sirokyp@ 123456vfu.cz
                Article
                parasite2012194p417 10.1051/parasite/2012194417
                10.1051/parasite/2012194417
                3671455
                23193527
                © PRINCEPS Editions, Paris, 2012

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                Page count
                Figures: 1, Tables: 2, Equations: 0, References: 35, Pages: 6
                Categories
                Original Contribution

                Comments

                Comment on this article