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      • Record: found
      • Abstract: found
      • Article: found

      Experimental Corneal Calcification. A Study of Transport of 45Ca into the Aqueous and Cornea

      research-article
      Author(s): ,
      Publication date (Electronic):
      Journal: Ophthalmic Research
      Publisher: S. Karger AG
      Keywords: Rabbit, Cornea, Calcification, Dihydrotachosterol, Transport-phenomena, Calcium, Aqueous humour, Corneal edema

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          Abstract

          Experimental corneal calcification has been produced in rabbits by a combination of corneal injury (perfusion of the anterior chamber with a solution of kalium permanganate) and dihydrotachysterol (DHT) treatment. Three groups of rabbits were compared: a group of animals pretreated with DHT and with perfusion of the anterior chamber of the left eye, a group of animals only injured, and a group of normal rabbits. Hydration of the corneas and penetration of intravenously injected <sup>45</sup>Ca into the aqueous, central and peripheral parts of corneas, were followed. The highest activity of aqueous and corneas of both eyes was found in rabbits treated with DHT. No significant difference between the radioactivity of the central and peripheral parts of the cornea was observed. Hydration of corneas in this group seemed to be less pronounced in comparison with the group of rabbits without DHT treatment.

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          Author and article information

          Journal
          Journal ID (publisher-id): ORE
          Journal ID (nlm-ta): Ophthalmic Res
          Journal ID (doi): 10.1159/issn.0030-3747
          Title: Ophthalmic Research
          Publisher: S. Karger AG
          ISSN (Print): 0030-3747
          ISSN (Electronic): 1423-0259
          Publication date Subscription-year: 1970
          Publication date (Print): 1970
          Publication date (Electronic): 27 November 2009
          Volume: 1
          Issue: 3
          Pages: 187-192
          Affiliations
          Eye Research Laboratory, Czechoslovak Academy of Sciences (Head: Prof.MUDr. F. Vrabec, DrSc), Prague, ČSSR and Central Isotopic Laboratories of the Institutes for Biological Research, Czechoslovak Academy of Sciences (Head: Doc. RNDr. Karel Vereš, CSc), Prague, ČSSR
          Article
          Publisher ID: 264516 Other ID: Ophthal Res 1970;1:187–192
          DOI: 10.1159/000264516
          SO-VID: 133a6820-5018-431f-b299-dc55d3e55658
          Copyright © © 1970 S. Karger AG, Basel
          License:

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          Page count
          Pages: 6
          Categories
          Subject: Paper

          ScienceOpen disciplines: Vision sciences,Ophthalmology & Optometry,Pathology
          Keywords: Calcium,Dihydrotachosterol,Corneal edema,Aqueous humour,Calcification,Cornea,Transport-phenomena,Rabbit
          Data availability:
          ScienceOpen disciplines: Vision sciences, Ophthalmology & Optometry, Pathology
          Keywords: Calcium, Dihydrotachosterol, Corneal edema, Aqueous humour, Calcification, Cornea, Transport-phenomena, Rabbit

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