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      Multiple pathways of cross-resistance to glycopeptides and daptomycin in persistent MRSA bacteraemia.

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          Abstract

          The development of non-susceptibility to glycopeptides and daptomycin in MRSA during persistent bacteraemia has become a significant therapeutic challenge. However, the in vivo evolution and mechanism of the dual resistance have remained incompletely understood.

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          Author and article information

          Journal
          J. Antimicrob. Chemother.
          The Journal of antimicrobial chemotherapy
          1460-2091
          0305-7453
          Nov 2015
          : 70
          : 11
          Affiliations
          [1 ] Division of Paediatric Infectious Diseases, Department of Paediatrics, Chang Gung Children's Hospital and Chang Gung Memorial Hospital, 333 Taoyuan, Taiwan College of Medicine, Chang Gung University, 333 Taoyuan, Taiwan james.ped@gmail.com.
          [2 ] Division of Paediatric Infectious Diseases, Department of Paediatrics, Chang Gung Children's Hospital and Chang Gung Memorial Hospital, 333 Taoyuan, Taiwan College of Medicine, Chang Gung University, 333 Taoyuan, Taiwan.
          Article
          dkv225
          10.1093/jac/dkv225
          26216581
          © The Author 2015. Published by Oxford University Press on behalf of the British Society for Antimicrobial Chemotherapy. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

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