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      Review of the Literature on Leiomyoma and Leiomyosarcoma of the Adrenal Gland: A Systematic Analysis of Case Reports

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          Abstract

          Background/Aim: To date few cases of smooth muscle-derived tumors of the adrenal gland have been reported and their treatment remains a medical challenge. The aim of this manuscript was to systematically review the literature and present the tumor characteristics and their management in order to provide a standardized approach to their diagnosis and management. Materials and Methods: We searched five databases (PubMed, Scopus, Elsevier, ResearchGate, Google scholar) for relevant articles published until March 2020. Results: Twenty-two cases of adrenal leiomyoma, four cases of adrenal smooth muscle tumor and forty-five cases of adrenal leiomyosarcoma were included. Conclusion: We present the demographic, clinical, radiological, pathological and oncological characteristics and prognosis of tumors of the adrenal gland arising from smooth muscle cells, as well as describe the common clinical investigations and therapeutic modalities that have been reported as part of their management.

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          Author and article information

          Journal
          In Vivo
          In Vivo
          In Vivo
          International Institute of Anticancer Research
          0258-851X
          1791-7549
          3 September 2020
          Sep-Oct 2020
          : 34
          : 5
          : 2233-2248
          Affiliations
          [1 ]Third Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece
          [2 ]Second Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, Aretaieion University Hospital, Athens, Greece
          [3 ]Department of Endocrinology, School of Medicine, National and Kapodistrian University of Athens, Attikon University Hospital, Athens, Greece
          [4 ]First Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, Laikon University Hospital, Athens, Greece
          Author notes
          Maria Sakellariou, MD, Third Department of Surgery, School of Medicine, National and Kapodistrian University of Athens, Attikon University Hospital, Rimini 1, Haidari, 12462, Athens, Greece. Tel: +30 6948404126 marisakellariou@ 123456gmail.com
          Article
          PMC7652436 PMC7652436 7652436
          10.21873/invivo.12034
          7652436
          32871746
          137fd6f3-b489-4a10-81af-801ce8940006
          Copyright 2020, International Institute of Anticancer Research
          History
          : 7 June 2020
          : 6 July 2020
          Categories
          Review Article

          review,adrenalectomy,smooth muscle tumor,leiomyosarcoma,leiomyoma,suprarenal,neoplasia,Adrenal gland

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