Recent research about mild cognitive impairment in China Translated title: 中国轻度认知功能损害的研究进展

Summary:

The rapid aging of the Chinese population has spurred interest in research about the cause and prevention of dementia and its precursor, mild cognitive impairment (MCI). This review summarizes the last decade of research in China about MCI. Extensive research about the epidemiology, neuropsychological characteristics, diagnosis, genetic etiology, neuroimaging and electrophysiological changes, and treatment of MCI has provided some new insights but few breakthroughs. Further advances in the prevention and treatment of MCI will require a greater emphasis on multi-disciplinary prospective studies with large, representative samples that use standardized methods to assess and monitor changes in cognitive functioning over time.

摘要：

中国人口的迅速老龄化促进了对老年痴呆及其前体（轻度认知功能损害，MCI）的病因和预防的研究。本文综述了过去十年中国有关MCI的研究。有关MCI的流行病学、神经心理特征、诊断学、遗传病因学、神经影像学和电生理变化以及治疗方面的广泛研究已提供了一些新的见解，但很少有突破结果。对于MCI的预防与治疗，未来的发展方向则更注重具有代表性的大样本多学科前瞻性研究，并使用标准化方法来评估和监测认知功能随着时间的推移而产生的变化。