Illness perception determines the healthy lifestyle of patients with Familial Hypercholesterolaemia (FH). Despite the availability of advanced treatment and preventive measures, there is still sparse data on illness perception of FH patients. Hence, this study aimed to describe the illness perception of FH patients and investigate its association with sociodemographic and illness-related factors. 100 FH patients were assessed using Pro forma questionnaires and revised illness perception questionnaire (IPQ-R). Illness perception of FH patients varies according to the level of education and the presence of cardiovascular disease (CVD). These findings may help clinicians to improve the interventions suitable for FH patients.