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      Ultracompact biochemical sensor built with two-dimensional photonic crystal microcavity.

      Optics letters
      Biosensing Techniques, instrumentation, methods, Equipment Design, Equipment Failure Analysis, Immunoassay, Miniaturization, Molecular Probe Techniques, Optics and Photonics, Photons, Protein Interaction Mapping, Refractometry, Spectrum Analysis, Transducers

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          Abstract

          We report an experimental demonstration of an ultracompact biochemical sensor based on a two-dimensional photonic crystal microcavity. The microcavity, fabricated on a silicon-on-insulator substrate, is designed to have a resonant wavelength (lambda) near 1.5 microm. The transmission spectrum of the sensor is measured with different ambient refractive indices ranging from n = 1.0 to n = 1.5. From observation of the shift in resonant wavelength, a change in ambient refractive index of delta(n) = 0.002 is readily apparent. The correspondence between absolute refractive index and resonant wavelength agrees with numerical calculation to within 4% accuracy. The evaporation of water in a 5% glycerol mixture is also used to demonstrate the capability for in situ time-resolved sensing.

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