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      Mandibular mass as the presenting manifestation of IgM myeloma in a 22-year-old man.

      1 , , , ,
      Annals of hematology

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          Abstract

          We report here the youngest known IgM myeloma patient to have presented with a mandibular mass. A 22-year-old Chinese man sought medical attention due to a mass over his right mandible that had been growing progressively for 6 months. A solitary osteolytic lesion in the right mandible was identified radiologically. Incisional biopsy revealed the presence of plasma cells of monoclonal origin, as evidenced by the exclusively positive staining of the kappa light chain. The diagnosis of multiple myeloma with mandibular involvement was confirmed by bone marrow examination. Further tests, including immunoglobulin electrophoresis and assay of the serum levels of kappa and lambda light chains, demonstrated that his myeloma was of the IgM, kappa subtype. The patient achieved a nonsustained partial response to six courses of melphalan and prednisolone therapy and palliative radiotherapy.

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          Author and article information

          Journal
          Ann. Hematol.
          Annals of hematology
          0939-5555
          0939-5555
          Feb 1999
          : 78
          : 2
          Affiliations
          [1 ] Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China.
          Article
          10089027
          14319374-9f84-4f02-a167-5c97a5dd2339
          History

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