Blog
About

41
views
0
recommends
+1 Recommend
0 collections
    4
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      A room temperature ionic liquid as convenient solvent for the oxidative folding of conopeptides.

      Journal of Peptide Science

      Temperature, chemistry, Solvents, metabolism, Sodium Channels, Rats, Protein Folding, genetics, Peptides, Oxidation-Reduction, Muscle Proteins, Molecular Sequence Data, Ions, Humans, Conotoxins, Cell Line, Animals, Amino Acid Sequence

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          We report the first example of conopeptide oxidation performed in a biocompatible ionic liquid, 1-ethyl-3-methylimidazolium acetate ([C(2)mim][OAc]), which enables the efficient formation of both hydrophilic and poorly water-soluble conotoxins compared with conventional methods. Moreover, the method features a high-concentration approach ultimately leading to higher yields at reduced separation effort. (c) 2008 European Peptide Society and John Wiley & Sons, Ltd.

          Related collections

          Author and article information

          Journal
          10.1002/psc.1106
          19089803

          Comments

          Comment on this article