6
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Magnetic Controlled Growth Rods in the Treatment of Scoliosis: Safety, Efficacy and Patient Selection

      review-article
      1 , 1
      Medical Devices (Auckland, N.Z.)
      Dove
      MAGEC, growth rods, early-onset, scoliosis, treatment

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Early-onset scoliosis is defined as a spinal curvature greater than 10° in children prior to 10 years of age. Untreated EOS may lead to progressively severe spinal deformity, impaired pulmonary development, restrictive lung disease, and both increased morbidity and mortality. Limitations of established conservative treatments include inability to correct severe deformity, as well as challenges with compliance when casting and bracing is applied. In addition, surgical treatment in the form of traditional growing rods requires regular surgical lengthenings and is associated with complications inherent with repeated invasive procedures and exposure to general anesthesia. MAGEC is an evolving magnetically controlled growing rod system for the treatment of EOS. After initial implantation, lengthening is achieved non-invasively by using magnetic external remote control. MAGEC offers the potential to control moderate and severe EOS, while avoiding repeated surgical procedures and associated complications. In this review, we examine the results from clinical, radiological and explant studies following the use of MAGEC, in the context of other established and emerging treatments for EOS.

          Related collections

          Most cited references56

          • Record: found
          • Abstract: found
          • Article: not found

          Long-term follow-up of patients with untreated scoliosis. A study of mortality, causes of death, and symptoms.

          The mortality and causes of death in 115 patients (80 women), born 1902-1937, with untreated scoliosis were compared to the expected according to official Swedish statistics. Subgrouping for cause and onset of scoliosis was done. Fifty-five patients had died; 21 of respiratory failure and 17 of cardiovascular diseases. The mortality was significantly (P less than 0.001) increased. The increased risk was apparent at 40-50 years of age. The mortality was significantly increased in infantile (P less than 0.001) and juvenile (P less than 0.01) scoliosis but not in adolescent scoliosis. The mortality was also increased in post-polio scoliosis, scoliosis combined with rickets and scoliosis of unknown etiology indicating an increased mortality in idiopathic scoliosis. Among the surviving patients anti-hypertensive treatment was frequent (23 of 50).
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Dual growing rod technique followed for three to eleven years until final fusion: the effect of frequency of lengthening.

            Retrospective case review of children completing dual growing rod treatment at our institutions. Patients had a minimum of 2 years follow-up. To identify the factors influencing dual growing rod treatment outcome followed to final fusion. Published reports on dual growing rod technique results for early onset scoliosis demonstrate it to be safe and effective in curve correction and maintenance as well as in allowing spinal growth. Between 1990 and 2003, 13 patients with no previous surgery and noncongenital curves underwent final fusion. All had preoperative curve progression over 10 degrees after unsuccessful nonoperative treatment. There were 10 females and 3 males. Average age was 6.6 +/- 2.9 years at initial surgery. There were 3 idiopathic, 1 nonspine congenital anomaly, and 9 syndromic patients. Analysis included age at initial surgery and final fusion, number and frequency of lengthenings, and complications. Radiographic evaluation included changes in Cobb angle, T1-S1 length, and instrumentation length over the treatment period. Cobb angle improved from 81.0 +/- 23 degrees to 35.8 +/- 15 degrees postinitial and 27.7 +/- 17 degrees after final fusion. Average number of lengthenings was 5.2 +/- 3 at an interval of 9.4 +/- 5 months. T1-S1 length increased from 24.4 +/- 3.4 to 29.3 +/- 3.6 cm postinitial and 35.0 +/- 3.7 cm postfinal fusion. Average growth was 1.46 +/- 0.66 cm/year. Those lengthened at
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              Early-Onset Scoliosis: A Review of History, Current Treatment, and Future Directions

                Bookmark

                Author and article information

                Journal
                Med Devices (Auckl)
                Med Devices (Auckl)
                MDER
                mder
                Medical Devices (Auckland, N.Z.)
                Dove
                1179-1470
                17 March 2020
                2020
                : 13
                : 75-85
                Affiliations
                [1 ]Scottish National Spine Deformity Center, Royal Hospital for Sick Children, University of Edinburgh , Edinburgh, UK
                Author notes
                Correspondence: Athanasios I Tsirikos Scottish National Spine Deformity Center, Royal Hospital for Sick Children , Sciennes Road, EdinburghEH9 1LF, UK Email atsirikos@hotmail.com
                Author information
                http://orcid.org/0000-0003-2339-5327
                Article
                198176
                10.2147/MDER.S198176
                7085947
                14bee145-bad2-4f09-b208-7439349590a2
                © 2020 Tsirikos and Roberts.

                This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php).

                History
                : 28 December 2019
                : 18 February 2020
                Page count
                Figures: 4, References: 69, Pages: 11
                Categories
                Review

                Biotechnology
                magec,growth rods,early-onset,scoliosis,treatment
                Biotechnology
                magec, growth rods, early-onset, scoliosis, treatment

                Comments

                Comment on this article