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      Utilization of deceased donors during a pandemic: An argument against using SARS‐CoV‐2 positive donors

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          Abstract

          SARS‐CoV‐2 has rapidly become an unprecedented pandemic that has impacted society, disrupted hospital functions, strained healthcare resources and impacted the lives of transplant professionals. Despite this, organ failure and the need for transplantation continues throughout the United States. Considering the perpetual scarcity of deceased donor organs, Kates et al present a viewpoint that advocates for the utilization of COVID‐19 positive donors in selected cases. We present a review of the current literature that details the potential negative consequences of COVID‐19 positive donors. The factors we consider include: 1) the risk of blood transmission SARS‐CoV‐2, 2) involvement of donor organs, 3) lack of effective therapies, 4) exposure of healthcare and recovery teams, 5) disease transmission and propagation, and 6) hospital resource utilization. While we acknowledge that transplantation fulfills the mission of saving lives, it is imperative to consider the consequences not only to our recipients, but also to the community and to healthcare workers, particularly in the absence of effective preventative or curative therapies. For these reasons, we believe the evidence and risks show that COVID‐19 infection should continue to remain a contraindication for donation, as has been the initial response of donation and transplantation societies.

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          Author and article information

          Contributors
          malay.shah@uky.edu
          Journal
          Am J Transplant
          Am. J. Transplant
          10.1111/(ISSN)1600-6143
          AJT
          American Journal of Transplantation
          John Wiley and Sons Inc. (Hoboken )
          1600-6135
          1600-6143
          05 May 2020
          : 10.1111/ajt.15969
          Affiliations
          [ 1 ] Department of Surgery Division of Abdominal Transplant Surgery University of Kentucky College of Medicine Lexington Kentucky
          [ 2 ] Department of Surgery Division of Transplantation Emory University School of Medicine Atlanta Georgia
          [ 3 ] Department of Medicine Division of Infectious Diseases University of Kentucky College of Medicine Lexington Kentucky
          [ 4 ] Department of Medicine Johns Hopkins University School of Medicine Baltimore Maryland
          [ 5 ] President & CEO, Mid‐America Transplant St. Louis Missouri
          [ 6 ] Department of Medicine Division of Hepatology University of Miami Miller School of Medicine Miami Florida
          Author notes
          [*] [* ] Correspondence

          Malay B. Shah

          Email: malay.shah@ 123456uky.edu

          Article
          AJT15969
          10.1111/ajt.15969
          7267604
          32368850
          15144f4b-f3ef-4744-98c7-21a7e1e889a7
          This article is protected by copyright. All rights reserved.

          This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

          History
          Page count
          Figures: 0, Tables: 0, Pages: 15, Words: 304
          Categories
          Personal Viewpoint
          Personal Viewpoint
          Custom metadata
          2.0
          accepted-manuscript
          Converter:WILEY_ML3GV2_TO_JATSPMC version:5.8.3 mode:remove_FC converted:03.06.2020

          Transplantation
          Transplantation

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