15
views
0
recommends
+1 Recommend
2 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Global monitoring of the impact of the COVID-19 pandemic through online surveys sampled from the Facebook user base

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Significance

          The University of Maryland Global COVID Trends and Impact Survey (UMD-CTIS), launched April 2020, is the largest remote global health monitoring system. This study includes ∼30 million responses through December 2020 from all 114 countries/territories with survey weights to adjust for nonresponse and demographics. Using self-reported cross-sectional survey data sampled daily from Facebook users, we confirm consistent demographics and COVID-19 symptoms. Our global model predicts local COVID-19 case trends. Importantly, one survey item strongly correlates with reported cases, demonstrating potential utility in locales with scant UMD-CTIS sampling or government data. Despite limitations resulting from sampling, nonresponse, coverage, and measurement error, UMD-CTIS has the potential to support existing monitoring systems for COVID-19 as well as other new as-yet-undefined global health threats.

          Abstract

          Simultaneously tracking the global impact of COVID-19 is challenging because of regional variation in resources and reporting. Leveraging self-reported survey outcomes via an existing international social media network has the potential to provide standardized data streams to support monitoring and decision-making worldwide, in real time, and with limited local resources. The University of Maryland Global COVID-19 Trends and Impact Survey (UMD-CTIS), in partnership with Facebook, has invited daily cross-sectional samples from the social media platform's active users to participate in the survey since its launch on April 23, 2020. We analyzed UMD-CTIS survey data through December 20, 2020, from 31,142,582 responses representing 114 countries/territories weighted for nonresponse and adjusted to basic demographics. We show consistent respondent demographics over time for many countries/territories. Machine Learning models trained on national and pooled global data verified known symptom indicators. COVID-like illness (CLI) signals were correlated with government benchmark data. Importantly, the best benchmarked UMD-CTIS signal uses a single survey item whereby respondents report on CLI in their local community. In regions with strained health infrastructure but active social media users, we show it is possible to define COVID-19 impact trajectories using a remote platform independent of local government resources. This syndromic surveillance public health tool is the largest global health survey to date and, with brief participant engagement, can provide meaningful, timely insights into the global COVID-19 pandemic at a local scale.

          Related collections

          Most cited references43

          • Record: found
          • Abstract: not found
          • Article: not found

          Fair Allocation of Scarce Medical Resources in the Time of Covid-19

            Bookmark
            • Record: found
            • Abstract: found
            • Article: found
            Is Open Access

            Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts

            Summary Background Isolation of cases and contact tracing is used to control outbreaks of infectious diseases, and has been used for coronavirus disease 2019 (COVID-19). Whether this strategy will achieve control depends on characteristics of both the pathogen and the response. Here we use a mathematical model to assess if isolation and contact tracing are able to control onwards transmission from imported cases of COVID-19. Methods We developed a stochastic transmission model, parameterised to the COVID-19 outbreak. We used the model to quantify the potential effectiveness of contact tracing and isolation of cases at controlling a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-like pathogen. We considered scenarios that varied in the number of initial cases, the basic reproduction number (R 0), the delay from symptom onset to isolation, the probability that contacts were traced, the proportion of transmission that occurred before symptom onset, and the proportion of subclinical infections. We assumed isolation prevented all further transmission in the model. Outbreaks were deemed controlled if transmission ended within 12 weeks or before 5000 cases in total. We measured the success of controlling outbreaks using isolation and contact tracing, and quantified the weekly maximum number of cases traced to measure feasibility of public health effort. Findings Simulated outbreaks starting with five initial cases, an R 0 of 1·5, and 0% transmission before symptom onset could be controlled even with low contact tracing probability; however, the probability of controlling an outbreak decreased with the number of initial cases, when R 0 was 2·5 or 3·5 and with more transmission before symptom onset. Across different initial numbers of cases, the majority of scenarios with an R 0 of 1·5 were controllable with less than 50% of contacts successfully traced. To control the majority of outbreaks, for R 0 of 2·5 more than 70% of contacts had to be traced, and for an R 0 of 3·5 more than 90% of contacts had to be traced. The delay between symptom onset and isolation had the largest role in determining whether an outbreak was controllable when R 0 was 1·5. For R 0 values of 2·5 or 3·5, if there were 40 initial cases, contact tracing and isolation were only potentially feasible when less than 1% of transmission occurred before symptom onset. Interpretation In most scenarios, highly effective contact tracing and case isolation is enough to control a new outbreak of COVID-19 within 3 months. The probability of control decreases with long delays from symptom onset to isolation, fewer cases ascertained by contact tracing, and increasing transmission before symptoms. This model can be modified to reflect updated transmission characteristics and more specific definitions of outbreak control to assess the potential success of local response efforts. Funding Wellcome Trust, Global Challenges Research Fund, and Health Data Research UK.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: found

              Attributes and predictors of long COVID

              Reports of long-lasting coronavirus disease 2019 (COVID-19) symptoms, the so-called 'long COVID', are rising but little is known about prevalence, risk factors or whether it is possible to predict a protracted course early in the disease. We analyzed data from 4,182 incident cases of COVID-19 in which individuals self-reported their symptoms prospectively in the COVID Symptom Study app1. A total of 558 (13.3%) participants reported symptoms lasting ≥28 days, 189 (4.5%) for ≥8 weeks and 95 (2.3%) for ≥12 weeks. Long COVID was characterized by symptoms of fatigue, headache, dyspnea and anosmia and was more likely with increasing age and body mass index and female sex. Experiencing more than five symptoms during the first week of illness was associated with long COVID (odds ratio = 3.53 (2.76-4.50)). A simple model to distinguish between short COVID and long COVID at 7 days (total sample size, n = 2,149) showed an area under the curve of the receiver operating characteristic curve of 76%, with replication in an independent sample of 2,472 individuals who were positive for severe acute respiratory syndrome coronavirus 2. This model could be used to identify individuals at risk of long COVID for trials of prevention or treatment and to plan education and rehabilitation services.
                Bookmark

                Author and article information

                Journal
                Proc Natl Acad Sci U S A
                Proc Natl Acad Sci U S A
                pnas
                PNAS
                Proceedings of the National Academy of Sciences of the United States of America
                National Academy of Sciences
                0027-8424
                1091-6490
                13 December 2021
                21 December 2021
                13 December 2021
                : 118
                : 51
                : e2111455118
                Affiliations
                [1] aDivision of Endocrinology, Boston Children’s Hospital , Boston, MA 02115;
                [2] bComputational Epidemiology Lab, Boston Children’s Hospital , Boston, MA 02115;
                [3] cHarvard Medical School , Boston, MA 02115;
                [4] dBroad Institute of Harvard and MIT , Cambridge, MA 02142;
                [5] eDepartment of Epidemiology, Boston University , Boston, MA 02118;
                [6] fJoint Program in Survey Methodology, University of Maryland , College Park, MD 20742;
                [7] gCenter for Geospatial Information Science, University of Maryland , College Park, MD 20742;
                [8] hMeta , Menlo Park, CA 94025;
                [9] iDepartment of Statistics, Ludwig-Maximilians-Universität , Munich 80539, Germany
                Author notes
                2To whom correspondence may be addressed. Email: christina.astley@ 123456childrens.harvard.edu .

                Edited by Ryan J. Tibshirani, Carnegie Mellon University, Pittsburgh, PA, and approved November 8, 2021 (received for review July 5, 2021)

                3F.K. and J.S.B. contributed equally to this work.

                Author contributions: C.M.A., E.L.C., F.K., and J.S.B. designed research; C.M.A., G.T., K.A. Mc Cord, B.R., and T.J.V. performed research; S.L.C., X.D., K.S., T.H.F., K.M.B., S.L.R., K.A. Morris, and F.K. contributed new reagents/analytic tools; C.M.A., G.T., K.A. Mc Cord, B.R., and T.J.V. analyzed data; and C.M.A., K.A. Mc Cord, and F.K. wrote the paper.

                1C.M.A., G.T., and K.A. Mc Cord contributed equally to this work.

                Author information
                https://orcid.org/0000-0002-5063-8470
                https://orcid.org/0000-0002-5626-7463
                https://orcid.org/0000-0002-6095-0193
                https://orcid.org/0000-0002-6864-9952
                https://orcid.org/0000-0003-1826-6600
                https://orcid.org/0000-0002-1592-6880
                https://orcid.org/0000-0002-7339-2645
                Article
                202111455
                10.1073/pnas.2111455118
                8713788
                34903657
                152119f3-9bdb-4038-8580-4eb7b903633d
                Copyright © 2021 the Author(s). Published by PNAS.

                This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).

                History
                : 08 November 2021
                Page count
                Pages: 10
                Funding
                Funded by: Facebook Sponsored Research Agreement
                Award ID: INB1116217
                Award Recipient : Christina M Astley Award Recipient : Gaurav Tuli Award Recipient : Kimberly A Mc Cord Award Recipient : Emily L Cohn Award Recipient : Benjamin Rader Award Recipient : Tanner J Varrelman Award Recipient : Samantha L Chiu Award Recipient : Xiaoyi Deng Award Recipient : Kathleen Stewart Award Recipient : Frauke Kreuter Award Recipient : John S Brownstein
                Funded by: Facebook Inc Grant No
                Award ID: 4332732
                Award Recipient : Christina M Astley Award Recipient : Gaurav Tuli Award Recipient : Kimberly A Mc Cord Award Recipient : Emily L Cohn Award Recipient : Benjamin Rader Award Recipient : Tanner J Varrelman Award Recipient : Samantha L Chiu Award Recipient : Xiaoyi Deng Award Recipient : Kathleen Stewart Award Recipient : Frauke Kreuter Award Recipient : John S Brownstein
                Categories
                408
                432
                548
                Biological Sciences
                Biophysics and Computational Biology
                Social Sciences
                Social Sciences
                Beyond Cases and Deaths: The Benefits of Auxiliary Data Streams In Tracking the COVID-19 Pandemic
                Custom metadata
                free

                covid-19 surveillance,global health,human social sensing,sars-cov-2 testing

                Comments

                Comment on this article