5
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Normal-conducting scaling fixed field alternating gradient accelerator for proton therapy

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Related collections

          Most cited references30

          • Record: found
          • Abstract: found
          • Article: not found

          Errors and margins in radiotherapy.

          Clinical radiotherapy procedures aim at high accuracy. However, there are many error sources that act during treatment preparation and execution that limit the accuracy. As a consequence, a safety margin is required to ensure that the planned dose is actually delivered to the target for (almost) all patients. Before treatment planning, a planning computed tomography scan is made. In particular, motion of skin with respect to the internal anatomy limits the reproducibility of this step, introducing a systematic setup error. The second important error source is organ motion. The tumor is imaged in an arbitrary position, leading to a systematic organ motion error. The image may also be distorted because of the interference of the scanning process and organ motion. A further systematic error introduced during treatment planning is caused by the delineation process. During treatment, the most important errors are setup error and organ motion leading to day-to-day variations. There are many ways to define the margins required for these errors. In this article, an overview is given of errors in radiotherapy and margin recipes, based on physical and biological considerations. Respiration motion is treated separately.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Radiological use of fast protons.

            R R Wilson (1946)
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Density resolution of proton computed tomography.

              Conformal proton radiation therapy requires accurate prediction of the Bragg peak position. Protons may be more suitable than conventional x-rays for this task since the relative electron density distribution can be measured directly with proton computed tomography (CT). However, proton CT has its own limitations, which need to be carefully studied before this technique can be introduced into routine clinical practice. In this work, we have used analytical relationships as well as the Monte Carlo simulation tool GEANT4 to study the principal resolution limits of proton CT. The noise level observed in proton CT images of a cylindrical water phantom with embedded tissue-equivalent density inhomogeneities, which were generated based on GEANT4 simulations, compared well with predictions based on Tschalar's theory of energy loss straggling. The relationship between phantom thickness, initial energy, and the relative electron density resolution was systematically investigated to estimate the proton dose needed to obtain a given density resolution. We show that a reasonable density resolution can be achieved with a relatively small dose, which is comparable to or even lower than that of x-ray CT.
                Bookmark

                Author and article information

                Journal
                PRABFM
                Physical Review Special Topics - Accelerators and Beams
                Phys. Rev. ST Accel. Beams
                American Physical Society (APS)
                1098-4402
                September 2015
                September 2015
                : 18
                : 9
                Article
                10.1103/PhysRevSTAB.18.094701
                1553ae1e-270e-40ec-b6c9-f56f0f3d1832
                © 2015

                http://creativecommons.org/licenses/by/3.0/

                History

                Comments

                Comment on this article