There was an error in the placement of the legends for Figures 3, 4, 5, and 9. The
correct legends are:
Figure 3. Identification of the sino atrial node.
Transverse micro-CT image of the free wall of the right atrium showing the sino atrial
node (A) in a rabbit heart stained with 7.5% I2KI for 3 days, with 3D rendering of
the heart showing the associated plane of interest. Corresponding volume rendering
(B) and Segmented 3D surface (C). Distance between red dots- 4.9 mm, blue dots- 2.5
mm. CT- crista terminalis, IVC- inferior vena cava, PM- pectinate muscle, RA- right
atrium, SAN- sinoatrial node, SNA- sinus node artery, SVC- superior vena cava. (Scale
bar represents 1 mm).
Figure 4. Comparison of existing and current models of the sino atrial node.
Existing model of the SAN in rabbit (modified from Dobrzynski et al. 2005) constructed
from immunohistochemically stained sections (A,C), superimposed onto a schematic representation
of the heart showing the SAN epicardial position (A), and its relationship with the
myocardium on the endocardial surface (C). Volume rendering of the current model in
rabbit of the SAN, showing its true position on the epicardial (B) and endocardial
(D) surfaces. Ao- Aorta, CS- coronary sinus, IVC- inferior vena cava, PA- pulmonary
artery, PM- pectinate muscle, PV- pulmonary veins, RA- right atrium, SAN- sinoatrial
node, SANP- sinoatrial node periphery, SVC- superior vena cava.
Figure 5. The atrioventricular conduction axis in rabbit.
Longitudinal micro-CT images showing the penetrating bundle (A,D) and His bundle (B,E)
in a rabbit heart stained with 7.5% I2KI for 3 days. Segmented 3D surfaces of atrioventricular
conduction axis, showing the anteriorly positioned His bundle (C) and its lateral
aspect (F). Distance between red dots- 1.1 mm, green dots- 7.8 mm. AOV- aortic valve,
HB- His bundle, IVC- interventricular septum, LBB- left bundle branch, LV- left ventricle,
PB- penetrating bundle, RBB- right bundle branch. (Scale bar represents 1 mm).
Figure 9. 3-dimensional representation of the Purkinje Network.
3 rabbit hearts stained with 7.5% I2KI for 3 days (A-C Rabbit Heart 1) and 3.75% I2KI
for 5 days (D-F Rabbit Heart 2, g-i Rabbit heart 3). Volume renderings viewed from
base to apex (A,D,G), with corresponding segmented 3D surfaces in transverse (B,E,H)
and longitudinal orientation (C,F,I). Volumes of segmented data- 4.2 mm3, 5.5 mm3,
15.8 mm3 respectively. Coloured dots represent Purkinje network maximum widths- distance
between green dots- 13.5 mm, red dots- 17.1 mm, blue dots- 14.4 mm. IVS- interventricular
septum, PM- papillary muscle.