Blog
About

0
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Spotted Sea Bass ( Lateolabrax maculatus) cftr, nkcc1a, nkcc1b and nkcc2: Genome-Wide Identification, Characterization and Expression Analysis Under Salinity Stress

      Read this article at

      ScienceOpenPublisher
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The Na +/K +/2Cl cotransporter (NKCC) and the cystic fibrosis transmembrane conductance regulator (CFTR) proteins play crucial roles in the transportation of Na + and Cl . In this study, we identified cftr, nkcc1a, nkcc1b and nkcc2 in spotted sea bass ( Lateolabrax maculatus) genomic and transcriptomic databases. We also characterized these genes via phylogenetic and structural analyses. The results showed that both cftr and nkcc were highly conservative in L. maculatus. Quantitative real-time polymerase chain reaction (qRT-PCR) analysis in ten tissues showed that cftr, nkcc1a and nkcc2 highly express in osmoregulatory organs such as gill, kidney and intestine. Furthermore, the expressions of cftr and nkcc1a in gill as well as nkcc2 in intestine were up-regulated by high salinity, indicating that these genes function potentially in osmoregulation. Our findings provided the insights into the cftr and nkcc functions in euryhaline teleost.

          Related collections

          Author and article information

          Journal
          JOUC
          Journal of Ocean University of China
          Science Press and Springer (China )
          1672-5182
          12 November 2019
          01 December 2019
          : 18
          : 6
          : 1470-1480
          Affiliations
          1College of Fisheries, Ocean University of China, Qingdao 266003, China
          2The Key Laboratory of Mariculture of Ministry of Education, Ocean University of China, Qingdao 266003, China
          Author notes
          *Corresponding author: LI Yun
          Article
          s11802-019-4114-0
          10.1007/s11802-019-4114-0
          Copyright © Ocean University of China, Science Press and Springer-Verlag GmbH Germany 2019.

          The copyright to this article, including any graphic elements therein (e.g. illustrations, charts, moving images), is hereby assigned for good and valuable consideration to the editorial office of Journal of Ocean University of China, Science Press and Springer effective if and when the article is accepted for publication and to the extent assignable if assignability is restricted for by applicable law or regulations (e.g. for U.S. government or crown employees).

          Product
          Self URI (journal-page): https://www.springer.com/journal/11802

          Comments

          Comment on this article