Larry N. Singh:
ORCID: https://orcid.org/0000-0002-2478-5864
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: Project administrationRole: SoftwareRole: SupervisionRole: ValidationRole:
VisualizationRole: Writing – original draftRole: Writing – review & editing
Brian Ennis:
ORCID: https://orcid.org/0000-0002-2653-5009
Role: Software
Bryn Loneragan:
ORCID: https://orcid.org/0000-0002-7861-0197
Role: Investigation
Noah L. Tsao:
ORCID: https://orcid.org/0000-0002-5743-0795
Role: Formal analysis
M. Isabel G. Lopez Sanchez:
ORCID: https://orcid.org/0000-0002-1528-5964
Role: Investigation
Jianping Li: Role: Investigation
Patrick Acheampong: Role: Investigation
Oanh Tran: Role: Resources
Ian A. Trounce: Role: InvestigationRole: Supervision
Yuankun Zhu:
ORCID: https://orcid.org/0000-0002-2455-9525
Role: Software
Prasanth Potluri: Role: Supervision
Beverly S. Emanuel:
ORCID: https://orcid.org/0000-0002-9207-6955
Role: Resources
Daniel J. Rader:
ORCID: https://orcid.org/0000-0002-9245-9876
Role: Resources
Zoltan Arany:
ORCID: https://orcid.org/0000-0003-1368-2453
Role: ResourcesRole: Supervision
Scott M. Damrauer:
ORCID: https://orcid.org/0000-0001-8009-1632
Role: Formal analysisRole: Supervision
Adam C. Resnick:
ORCID: https://orcid.org/0000-0003-0436-4189
Role: Resources
Stewart A. Anderson: Role: Funding acquisitionRole: ResourcesRole: Supervision
Douglas C. Wallace:
ORCID: https://orcid.org/0000-0002-7480-8278
Role: Funding acquisitionRole: Resources
Manja Marz: Role: Editor
Journal ID (nlm-ta): PLoS Comput Biol
Journal ID (iso-abbrev): PLoS Comput Biol
Journal ID (publisher-id): plos
Title:
PLoS Computational Biology
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-734X
ISSN
(Electronic):
1553-7358
Publication date
(Electronic):
11
November
2021
Publication date Collection:
November
2021
Volume: 17
Issue: 11
Electronic Location Identifier: e1009594
Affiliations
[1
]
Center for Mitochondrial and Epigenomic Medicine, Division of Human Genetics, The
Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of
America
[2
]
Center for Data-Driven Discovery in Biomedicine (D3b), The Children’s Hospital of
Philadelphia, Philadelphia, Pennsylvania, United States of America
[3
]
Center for Eye Research Australia, Ophthalmology, Department of Surgery, University
of Melbourne, Melbourne, Australia
[4
]
Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia,
Pennsylvania, United States of America
[5
]
Department of Psychiatry, The Children’s Hospital of Philadelphia and the University
of Pennsylvania, Philadelphia, Pennsylvania, United States of America
[6
]
22q and You Center, Division of Human Genetics, The Children’s Hospital of Philadelphia
and the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
[7
]
Regeneron Genetics Center, Tarrytown, New York, United States of America
[8
]
Department of Genetics, Perelman School of Medicine, University of Pennsylvania, Philadelphia,
Pennsylvania, United States of America
[9
]
Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania,
Philadelphia, Pennsylvania, United States of America
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PCOMPBIOL-D-21-00835
DOI: 10.1371/journal.pcbi.1009594
PMC ID: 8610268
PubMed ID: 34762648
SO-VID: 166743cd-4dfe-42c1-8913-a6d5348b2bed
Copyright © © 2021 Singh et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by:
funder-id http://dx.doi.org/10.13039/100000025, National Institute of Mental Health;
Award ID: MH110185
Award Recipient
:
Stewart A. Anderson
Funded by:
funder-id http://dx.doi.org/10.13039/100000065, National Institute of Neurological Disorders and Stroke;
Award ID: NS021328
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7480-8278
Douglas C. Wallace
Funded by:
funder-id http://dx.doi.org/10.13039/100000025, National Institute of Mental Health;
Award ID: MH108592
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7480-8278
Douglas C. Wallace
Funded by:
funder-id http://dx.doi.org/10.13039/100000052, NIH Office of the Director;
Award ID: OD010944
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7480-8278
Douglas C. Wallace
This work was supported by grants awarded to SA (National Institutes of Mental Health
- MH110185) and DCW (National Institute of Neurological Disorders and Stroke: NS021328,
National Institutes of Mental Health: MH108592, and Office of the Director: OD010944).
The funders had no role in study design, data collection and analysis, decision to
publish, or preparation of the manuscript.
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