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      Ultrasound and screening tool for dengue fever

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      1 , , 2
      Polish Journal of Radiology
      Termedia Publishing House

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          Abstract

          Dear Editor, We read the publication “Ultrasound is not useful as a screening tool for dengue fever” with great interest. Parmar et al. noted that “increased gall bladder wall thickness, pleural effusion, ascites, hepatomegaly, and splenomegaly are highly suggestive of dengue fever in clinically suspected cases. However, ultrasound should not be used as a screening tool, as negative ultrasound findings cannot rule out dengue fever due to the low sensitivity of this examination [1]”. We would like to share our ideas and experience on using ultrasound for diagnosis of dengue in our setting, tropical Indochina, where dengue is highly prevalent. Ultrasound is not routinely recommended for diagnosis of dengue. The basic screening tool is the tourniquet test, which is helpful for diagnosis of thrombocytopaenia [2]. The abdominal ultrasound investigation in dengue patients usually gives a negative finding. Positive findings are usually observed in severe cases in which a simple clinical examination combining simple laboratory investigations, complete blood count, and dengue immunological test can help in the diagnosis. Also, the mentioned positive findings, such as thickening gall bladder or hepatomegaly, can also be seen in other tropical infections such as viral hepatitis [3]. It can be concluded that ultrasound is not appropriate and not cost effective for screening of dengue fever. Conflict of interest The authors report no conflict of interest.

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          The tourniquet test is still a good screening tool for dengue illness.

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            Ultrasound is Not Useful as a Screening Tool for Dengue Fever

            Summary Background Dengue fever is a tropical disease that is transmitted by female Aedes Aegypti mosquitos. Early diagnosis is necessary to reduce the mortality and morbidity associated with the disease. A combination of clinical, laboratory, and sonography findings can be potentially helpful in making an early diagnosis of dengue fever. There is paucity of literature on the use of ultrasound for dengue fever screening; hence, the primary objective of the study was to evaluate the utility of ultrasound as a screening tool in dengue fever. Material/Methods A total of 160 patients of suspected dengue fever were included in the study. They underwent ultrasound examinations in order to search for thickening of the gallbladder wall, pleural effusion, and ascites. On the basis of ultrasound findings, 65 cases were positive and 95 cases were negative for dengue fever. Serological tests were also used for diagnosing dengue fever, 93 cases were seropositive and 67 cases were seronegative. The ultrasonically diagnosed cases were compared with serologically diagnosed cases, and appropriate descriptive statistical analyses were applied. Results The ultrasound findings included gall bladder wall thickening in 66 patients (41.2%). The sensitivity, specificity, and positive predictive value of ultrasound in diagnosing dengue fever were 58%, 84%, and 83%, respectively. The negative predictive value and accuracy were 59% and 68.8%, respectively. Conclusions The present study suggests that increased gall bladder wall thickness, pleural effusion, ascites, hepatomegaly, and splenomegaly are highly suggestive of dengue fever in clinically suspected cases. However, ultrasound should not be used as a screening tool, as negative ultrasound findings cannot rule out dengue fever due to the low sensitivity of this examination.
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              Letter to Editor Commenting on "Patterns of Gall Bladder Wall Thickening in Dengue Fever".

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                Author and article information

                Journal
                Pol J Radiol
                Pol J Radiol
                PJR
                Polish Journal of Radiology
                Termedia Publishing House
                1733-134X
                1899-0967
                19 December 2018
                2018
                : 83
                : e587
                Affiliations
                [1 ]Medical Academic Centre, Bangkok, Thailand
                [2 ]DY Patil University, Pune, India
                Author notes
                Correspondence address: Beuy Joob, Medical Academic Centre, Bangkok, Thailand. e-mail: beuyjoob@ 123456hotmail.com
                Article
                81253
                10.5114/pjr.2018.81253
                6384398
                16a2e53c-e2da-4445-bae2-75aeb535ebae
                Copyright © Polish Medical Society of Radiology 2018

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0). License allowing third parties to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.

                History
                : 08 October 2018
                : 17 October 2018
                Categories
                Letter to the Editor

                Radiology & Imaging
                Radiology & Imaging

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