We report the case of a 38-year-old man with known human immunodeficiency virus infection who presented with severe Bordetella Bronchiseptica pneumoniae that led to septic shock and acute renal insufficiency, after which he developed bilateral cortical nephrocalcinosis, affecting most severely the right kidney with associated atrophy. The onset and progressive development of the findings were documented via both ultrasound and computed tomography. As far as we know, this is the first time that the development of cortical nephrocalcinosis has been documented via imaging, interestingly revealing a gradual decrease of the right kidney size, together with a change from a punctate pattern of cortical calcifications to a rim of calcifications