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      Biogenic synthesis of silver nanoparticles and their antioxidant and antibacterial activity

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      Applied Nanoscience
      Springer Nature

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          Nanosilver as a new generation of nanoproduct in biomedical applications.

          Nanosilver (NS), comprising silver nanoparticles, is attracting interest for a range of biomedical applications owing to its potent antibacterial activity. It has recently been demonstrated that NS has useful anti-inflammatory effects and improves wound healing, which could be exploited in developing better dressings for wounds and burns. The key to its broad-acting and potent antibacterial activity is the multifaceted mechanism by which NS acts on microbes. This is utilized in antibacterial coatings on medical devices to reduce nosocomial infection rates. Many new synthesis methods have emerged and are being evaluated for NS production for medical applications. NS toxicity is also critically discussed to reflect on potential concerns before widespread application in the medical field. Copyright © 2010 Elsevier Ltd. All rights reserved.
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            Functional Materials in Food Nanotechnology

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              The green synthesis, characterization and evaluation of the biological activities of silver nanoparticles synthesized from Iresine herbstii leaf aqueous extracts.

              Silver has been used since time immemorial in different chemical form to treat burns, wounds and several infections caused by pathogenic bacteria. Advancement of biological process of nanoparticles synthesis is evolving into a key area of nanotechnology. The current study deals with the synthesis, characterization of silver nanoparticles using Iresine herbstii and evaluation of their antibacterial, antioxidant and cytotoxic activity. The reaction mixture turned to brownish gray color after 7 days of incubation and exhibits an absorbance peak around 460 nm characteristic of Ag nanoparticle. Scanning electron microscopy (SEM) and EDX analysis showed silver nanoparticles were pure and polydispersed and the size were ranging from 44 to 64 nm. X-ray diffraction (XRD) studies revealed that most of the nanoparticles were cubic and face centered cubic in shape. Fourier transform infrared spectroscopy (FTIR) showed nanoparticles were capped with plant compounds. Biosynthesized silver nanoparticles showed potent antibacterial activity against human pathogenic bacteria. Phytosynthesized nanoparticles exhibited strong antioxidant activity as well as cytotoxicity against HeLa cervical cell lines. The approach of green synthesis seems to be cost efficient, eco-friendly and easy alternative to conventional methods of silver nanoparticles synthesis. The powerful bioactivity demonstrated by the synthesized silver nanoparticles leads towards the clinical use as antibacterial, antioxidant as well as cytotoxic agent.
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                Author and article information

                Journal
                Applied Nanoscience
                Appl Nanosci
                Springer Nature
                2190-5509
                2190-5517
                June 2016
                July 4 2015
                June 2016
                : 6
                : 5
                : 755-766
                Article
                10.1007/s13204-015-0473-z
                171cf0a4-cda2-4dda-943a-30f13568204a
                © 2016

                http://creativecommons.org/licenses/by/4.0

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