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Biodegradable Polymer Blend Based Surgical Sealant with Body Temperature Mediated Adhesion
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Abstract
The development of practical and efficient surgical sealants has the propensity to
improve operational outcomes. A biodegradable polymer blend is fabricated as a nonwoven
fiber mat in situ. After direct deposition onto the tissue of interest, the material
transitions from a fiber mat to a film. This transition promotes polymer-substrate
interfacial interactions leading to improved adhesion and surgical sealant performance.