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      Sharing Alcoholic Drinks and a COVID-19 Outbreak

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          Abstract

          COVID-19, the new respiratory infection, has spread from China to more than 100 countries (Hsia, 2020). Alcohol-containing hand sanitizer is part of the strategy to prevent person-to-person transmission. In Thailand, we have witnessed the incorrect belief that drinking alcohol can prevent COVID-19. We made the following observation from a group of COVID patients in Thailand (six females and five males, aged 25–28 years old). These patients had joined the same farewell party and drank alcoholic beverage by using the same glass. The cluster of outbreak among these patients occurred within 1 week after the farewell party. The disease investigation showed that there were four other persons joining that party but who did not drink. Those four persons did not develop illness. The incident illustrates that drinking alcoholic beverage does not help prevent COVID-19: the alcoholic concentration in alcoholic beverage is not high enough to kill the virus. In fact, in animal models, alcoholic consumption can cause immune impairment and increased susceptibility to respiratory virus (Meyerholz et al., 2008). It is well-established that the virus is shed in oral pharyngeal secretion and sputum, so it is not surprising that infection spread among individuals who shared a drinking glass. Conflict of interest None.

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          Most cited references2

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          Emerging new coronavirus infection in Wuhan, China: Situation in early 2020

          W Hsia (2020)
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            Chronic alcohol consumption increases the severity of murine influenza virus infections.

            Respiratory infections with both seasonal as well as potential pandemic Influenza viruses represent a significant burden on human health. Furthermore, viruses such as Influenza are increasingly recognized as important etiologic agents in community acquired pneumonia. Within the U.S. alone, approximately 12.9 million people are heavy drinkers and chronic abuse of alcohol is known to increase the risk and severity of community acquired pneumonia. Given the lack of knowledge regarding Influenza disease in this population, we determined the effects of chronic alcohol consumption on Influenza virus infection. Herein, we report that mice exposed to chronic ethanol have sharp increases in morbidity, mortality, and pulmonary virus titers relative to controls. These increases in influenza severity correspond with inhibited pulmonary influenza-specific CD8 T cell responses. Further, chronic ethanol consumption results in an enhanced pulmonary lesion severity, similar to that recently described for pandemic influenzas. Together, our results suggest that chronic alcohol consumption may increase the risk for severe influenza virus infections by altering the pulmonary inflammatory environment and CD8 T cell response.
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              Author and article information

              Journal
              Alcohol Alcohol
              Alcohol Alcohol
              alcalc
              Alcohol and Alcoholism (Oxford, Oxfordshire)
              Oxford University Press
              0735-0414
              1464-3502
              13 May 2020
              : agaa028
              Affiliations
              [1 ] 26 Medical Center , Bangkok Thailand
              [2 ] Dr DY Patil University , Pune, India
              [3 ] Hainan Medical University , Haikou, China
              Author notes
              Corresponding author: E-mail: rujittika@ 123456gmail.com
              Article
              agaa028
              10.1093/alcalc/agaa028
              7239261
              32400850
              17b5b3e5-52f2-4ae7-8e74-559ca4ebed11
              © The Author(s) 2020. Medical Council on Alcohol and Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

              This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

              This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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              Health & Social care
              Health & Social care

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