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The mosaic of autoimmunity.

Publication date: 1989-03-31

Keywords: Animals, Autoimmune Diseases, etiology, HLA Antigens, genetics, Hormones, immunology, Humans, Immunologic Deficiency Syndromes, Models, Biological

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Abstract

The term 'autoimmune' is applied to a wide spectrum of diseases, which, although they may differ in pathology, share many factors. In their review, portrayed as a mosaic, Yehuda Shoenfeld and David Isenberg illustrate the complexity of these conditions, outlining the many pieces, genetic, hormonal, immunological and environmental that contribute to auto-immunity, and show how their varying combinations lead to diverse diseases.