0
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Origins of Renal Physiology in the USA

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Research in renal physiology began later in the USA than in Europe. Initial studies in the early 1900s dealt with the pathophysiology of renal failure. Micropuncture study of single nephron function was initiated in the laboratory of A.N. Richards in the early 1920s and with the later addition of microperfusion provided important insights into the site and mechanisms of solute transport. In parallel, with the leadership of Homer Smith, the development of noninvasive clearance methods to measure glomerular filtration rate and renal blood flow initiated a fruitful period of quantification of renal hemodynamics and of transport by the tubules. The steady progress of renal physiology in the USA owes much to the generous support of basic reasearch by the National Institutes of Health. It is also worthy of mention that progress in renal physiology in the US owes much to work carried out in clinical departments and to the type of comparative studies exemplified by work at the Mt. Desert Island Biological Laboratory.

          Related collections

          Most cited references 1

          • Record: found
          • Abstract: not found
          • Article: not found

          Introduction

            Bookmark

            Author and article information

            Journal
            AJN
            Am J Nephrol
            10.1159/issn.0250-8095
            American Journal of Nephrology
            S. Karger AG
            978-3-8055-6855-5
            978-3-318-00128-0
            0250-8095
            1421-9670
            1999
            April 1999
            23 April 1999
            : 19
            : 2
            : 266-273
            Affiliations
            Department of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Conn., USA
            Article
            13460 Am J Nephrol 1999;19:266–273
            10.1159/000013460
            10213827
            © 1999 S. Karger AG, Basel

            Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

            Page count
            Figures: 6, Tables: 3, References: 57, Pages: 8
            Product
            Self URI (application/pdf): https://www.karger.com/Article/Pdf/13460
            Categories
            Origins of Renal Physiology (Dedicated to Carl Gottschalk)

            Comments

            Comment on this article