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      • Abstract: found
      • Article: found

      Spindleform Scleropathy: Collagen Changes of the Sclera

      Ophthalmic Research
      S. Karger AG
      Sclera, Malignant melanoma, Spindleform scleropathy, Vicinal glycol

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          To our knowledge, this is the first pathologic report of inter scleral collagen bundle changes occurring as well-defined spindleform lesions randomly interspersed within the sclera. The lesions were observed in an otherwise healthy 75-year-old man whose eye was enucleated because of a uveal malignant melanoma. There are few reports in the literature of focal scleral changes of a predominantly acid mucopolysaccharide nature. The entity we observed in this case differs from these reports by its spindleform appearance, random distribution (not overlying the melanoma) and predominantly vicinal glycol nature. Histopathologic, histochemical, and ultrastructural studies revealed that the lesions were not the result of mucoid degeneration of the scleral collagen and not an abnormal collagen structure.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          10 December 2009
          : 24
          : 3
          : 155-161
          Department of Ocular Pathology, University of Munich Eye Hospital, Munich, FRG
          267162 Ophthalmic Res 1992;24:155–161
          © 1992 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          : 02 May 1991
          : 20 January 1992
          Page count
          Pages: 7
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Sclera,Spindleform scleropathy,Vicinal glycol,Malignant melanoma


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