Prognostic Value of Thallium-201 Exercise Scintigraphy in Low-Risk Patients after Q-Wave Myocardial Infarction: Comparison with Exercise Testing and Catheterization

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Abstract

In a prospective study of 100 consecutive patients discharged after a Q-wave myocardial infarction, the value of reversible ischemia on thallium-201 scintigraphy to assess the risk of cardiac events (death or reinfarction) during 4 years was compared with variables from exercise testing and cardiac catheterization. Patients with markedly impaired left ventricular function [ejection fraction (EF) ≤0.30] were excluded. During follow-up there were 20 cardiac events (10 cardiac deaths and 10 reinfarctions). Thallium-201 scintigraphy was significantly better than all exercise test variables and better than an EF < 0.40, with good sensitivity and specificity (75 and 51%, respectively). Exercise-induced reversible ischemia on scintigraphy yielded the same information as the presence of multivessel disease. Exercise test variables were of limited value to assess prognosis. Thus, thallium-201 scintigraphy can be used as the only tool to predict future cardiac events in low-risk patients after a Q-wave myocardial infarction.

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Author and article information

Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1992

Publication date (Print): 1992

Publication date (Electronic): 14 November 2008

Volume: 81

Issue: 6

Pages: 342-350

Affiliations

Departments of ^aCardiology, ^bBiostatistics, and ^cNuclear Medicine, Free University, Hospital, Amsterdam, The Netherlands

Article

Publisher ID: 175828 Other ID: Cardiology 1992;81:342–350

DOI: 10.1159/000175828

PubMed ID: 1304416

SO-VID: 186c5340-718e-4961-ab41-8fb16441042a

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History

Date received : 17 July 1992

Date accepted : 28 August 1992

Page count

Pages: 9

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