Contributors
Federica Giordani:
ORCID: https://orcid.org/0000-0001-9964-281X
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: ValidationRole: VisualizationRole: Writing – original draftRole:
Writing – review & editing
Daniel Paape:
ORCID: https://orcid.org/0000-0003-4355-8058
Role: Formal analysisRole: InvestigationRole: Project administrationRole: ValidationRole:
Writing – original draft
Isabel M. Vincent:
ORCID: https://orcid.org/0000-0003-2663-4389
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
MethodologyRole: Writing – review & editing
Andrew W. Pountain:
ORCID: https://orcid.org/0000-0001-9651-5145
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
SoftwareRole: VisualizationRole: Writing – review & editing
Fernando Fernández-Cortés:
ORCID: https://orcid.org/0000-0001-9362-2164
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole:
Writing – review & editing
Eva Rico: Role: InvestigationRole: MethodologyRole: Validation
Ning Zhang: Role: ConceptualizationRole: InvestigationRole: Methodology
Liam J. Morrison:
ORCID: https://orcid.org/0000-0002-8304-9066
Role: ConceptualizationRole: Funding acquisitionRole: ValidationRole: Writing – review
& editing
Yvonne Freund: Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: Writing
– review & editing
Michael J. Witty:
ORCID: https://orcid.org/0000-0003-4094-7154
Role: ConceptualizationRole: Funding acquisitionRole: Writing – review & editing
Rosemary Peter: Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
Writing – review & editing
Darren Y. Edwards:
ORCID: https://orcid.org/0000-0001-8245-8928
Role: InvestigationRole: MethodologyRole: Validation
Jonathan M. Wilkes: Role: Formal analysisRole: MethodologyRole: Software
Justin J. J. van der Hooft:
ORCID: https://orcid.org/0000-0002-9340-5511
Role: Data curationRole: MethodologyRole: Writing – review & editing
Clément Regnault: Role: Data curationRole: InvestigationRole: Methodology
Kevin D. Read:
ORCID: https://orcid.org/0000-0002-8536-0130
Role: ConceptualizationRole: MethodologyRole: Validation
David Horn:
ORCID: https://orcid.org/0000-0001-5173-9284
Role: ConceptualizationRole: InvestigationRole: SupervisionRole: Writing – review
& editing
Mark C. Field:
ORCID: https://orcid.org/0000-0002-4866-2885
Role: Formal analysisRole: MethodologyRole: SupervisionRole: Writing – review & editing
Michael P. Barrett:
ORCID: https://orcid.org/0000-0001-9447-3519
Role: ConceptualizationRole: Funding acquisitionRole: Project administrationRole:
ResourcesRole: SupervisionRole: Writing – review & editing
Dominique Soldati-Favre: Role: Editor
Journal
Journal ID (nlm-ta): PLoS Pathog
Journal ID (iso-abbrev): PLoS Pathog
Journal ID (publisher-id): plos
Journal ID (pmc): plospath
Title:
PLoS Pathogens
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Print):
1553-7366
ISSN
(Electronic):
1553-7374
Publication date
(Electronic):
3
November
2020
Publication date Collection:
November
2020
Volume: 16
Issue: 11
Electronic Location Identifier: e1008932
Affiliations
[1
]
Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and
Inflammation, University of Glasgow, Glasgow, United Kingdom
[2
]
Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University
of Dundee, Dundee, United Kingdom
[3
]
Roslin Institute, Royal (Dick) School of Veterinary Studies, University of Edinburgh,
Midlothian, United Kingdom
[4
]
Anacor Pharmaceuticals, Inc., Palo Alto, California, United States of America
[5
]
Global Alliance for Livestock and Veterinary Medicine, Pentlands Science Park, Penicuik,
Edinburgh, United Kingdom
[6
]
Glasgow Polyomics, Institute of Infection, Immunity and Inflammation, College of Medical,
Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
[7
]
Current address: Bioinformatics Group, Wageningen University, Wageningen, the Netherlands
[8
]
Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, České
Budějovice, Czech Republic
University of Geneva, SWITZERLAND
Author notes
The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PPATHOGENS-D-20-00932
DOI: 10.1371/journal.ppat.1008932
PMC ID: 7710103
PubMed ID: 33141865
SO-VID: 18ba9708-5f91-44ff-843c-c00da18a58cf
Copyright © © 2020 Giordani et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 1
June
2020
Date
accepted
: 25
August
2020
Page count
Figures: 5,
Tables: 0,
Pages: 20
Funding
Funded by: funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/S001034/1
Award Recipient
:
ORCID: https://orcid.org/0000-0002-8304-9066
Liam J. Morrison
Funded by: funder-id http://dx.doi.org/10.13039/501100000268, Biotechnology and Biological Sciences Research Council;
Award ID: BB/S001034/1)
Award Recipient
:
ORCID: https://orcid.org/0000-0001-9447-3519
Michael P. Barrett
Funded by: funder-id http://dx.doi.org/10.13039/100004440, Wellcome Trust;
Award ID: 100320/Z/12/Z
Award Recipient
:
ORCID: https://orcid.org/0000-0001-5173-9284
David Horn
Funded by: funder-id http://dx.doi.org/10.13039/100004440, Wellcome Trust;
Award ID: 203134/Z/16/Z
Award Recipient
:
ORCID: https://orcid.org/0000-0001-5173-9284
David Horn
Funded by: funder-id http://dx.doi.org/10.13039/100004440, Wellcome Trust;
Award ID: 104111/Z/14/Z
Award Recipient
:
ORCID: https://orcid.org/0000-0001-9447-3519
Michael P. Barrett
This work was funded by a BBSRC grant (BB/S001034/1) and Global Alliance for Livestock
Veterinary Medicine (GALVmed) with funding from BMGF and UKAID grant (OPP-1093639)
to L.J.M. and M.P.B., a Wellcome Trust Senior Investigator Award to D.H. (100320/Z/
12/Z), a Wellcome Trust Centre Award (203134/Z/ 16/Z) to Dundee and a core grant to
the Wellcome Centre for Integrative Parasitology (104111/Z/14/ Z). The funders had
no role in study design, data collection and analysis, decision to publish, or preparation
of the manuscript.
Categories
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Protozoans
Subject:
Parasitic Protozoans
Subject:
Trypanosoma
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Protozoans
Subject:
Parasitic Protozoans
Subject:
Trypanosoma
Subject:
Trypanosoma Brucei
Subject:
Trypanosoma Brucei Gambiense
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Organic Compounds
Subject:
Amino Acids
Subject:
Hydroxyl Amino Acids
Subject:
Serine
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Organic Chemistry
Subject:
Organic Compounds
Subject:
Amino Acids
Subject:
Hydroxyl Amino Acids
Subject:
Serine
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Amino Acids
Subject:
Hydroxyl Amino Acids
Subject:
Serine
Subject:
Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Cloning
Subject:
Research and Analysis Methods
Subject:
Molecular Biology Techniques
Subject:
Cloning
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Protozoans
Subject:
Parasitic Protozoans
Subject:
Trypanosoma
Subject:
Trypanosoma Brucei
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Eukaryota
Subject:
Protozoans
Subject:
Parasitic Protozoans
Subject:
Trypanosoma
Subject:
Trypanosoma Congolense
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
RNA interference
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
RNA interference
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Genetic interference
Subject:
RNA interference
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
RNA interference
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