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      Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group

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          Abstract

          Background

          The past two decades have witnessed a surge in the use of lumbar facet blocks and radiofrequency ablation (RFA) to treat low back pain (LBP), yet nearly all aspects of the procedures remain controversial.

          Methods

          After approval by the Board of Directors of the American Society of Regional Anesthesia and Pain Medicine, letters were sent to a dozen pain societies, as well as representatives from the US Departments of Veterans Affairs and Defense. A steering committee was convened to select preliminary questions, which were revised by the full committee. Questions were assigned to 4–5 person modules, who worked with the Subcommittee Lead and Committee Chair on preliminary versions, which were sent to the full committee. We used a modified Delphi method, whereby the questions were sent to the committee en bloc and comments were returned in a non-blinded fashion to the Chair, who incorporated the comments and sent out revised versions until consensus was reached.

          Results

          17 questions were selected for guideline development, with 100% consensus achieved by committee members on all topics. All societies except for one approved every recommendation, with one society dissenting on two questions (number of blocks and cut-off for a positive block before RFA), but approving the document. Specific questions that were addressed included the value of history and physical examination in selecting patients for blocks, the value of imaging in patient selection, whether conservative treatment should be used before injections, whether imaging is necessary for block performance, the diagnostic and prognostic value of medial branch blocks (MBB) and intra-articular (IA) injections, the effects of sedation and injectate volume on validity, whether facet blocks have therapeutic value, what the ideal cut-off value is for a prognostic block, how many blocks should be performed before RFA, how electrodes should be oriented, the evidence for larger lesions, whether stimulation should be used before RFA, ways to mitigate complications, if different standards should be applied to clinical practice and clinical trials and the evidence for repeating RFA (see table 12 for summary).

          Conclusions

          Lumbar medial branch RFA may provide benefit to well-selected individuals, with MBB being more predictive than IA injections. More stringent selection criteria are likely to improve denervation outcomes, but at the expense of more false-negatives. Clinical trials should be tailored based on objectives, and selection criteria for some may be more stringent than what is ideal in clinical practice.

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          Most cited references327

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          Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity.

          To develop and validate a new risk-of-bias tool for nonrandomized studies (NRSs). We developed the Risk of Bias Assessment Tool for Nonrandomized Studies (RoBANS). A validation process with 39 NRSs examined the reliability (interrater agreement), validity (the degree of correlation between the overall assessments of RoBANS and Methodological Index for Nonrandomized Studies [MINORS], obtained by plotting the overall risk of bias relative to effect size and funding source), face validity with eight experts, and completion time for the RoBANS approach. RoBANS contains six domains: the selection of participants, confounding variables, the measurement of exposure, the blinding of the outcome assessments, incomplete outcome data, and selective outcome reporting. The interrater agreement of the RoBANS tool except the measurement of exposure and selective outcome reporting domains ranged from fair to substantial. There was a moderate correlation between the overall risks of bias determined using RoBANS and MINORS. The observed differences in effect sizes and funding sources among the assessed studies were not correlated with the overall risk of bias in these studies. The mean time required to complete RoBANS was approximately 10 min. The external experts who were interviewed evaluated RoBANS as a "fair" assessment tool. RoBANS shows moderate reliability, promising feasibility, and validity. The further refinement of this tool and larger validation studies are required. Copyright © 2013 Elsevier Inc. All rights reserved.
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            Analysis of tissue and arterial blood temperatures in the resting human forearm.

            H H PENNES (1948)
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              A review of psychological risk factors in back and neck pain.

              S J Linton (2000)
              The literature on psychological factors in neck and back pain was systematically searched and reviewed. To summarize current knowledge concerning the role of psychological variables in the etiology and development of neck and back pain. Recent conceptions of spinal pain, especially chronic back pain, have highlighted the role of psychological factors. Numerous studies subsequently have examined the effects of various psychological factors in neck and back pain. There is a need to review this material to ascertain what conclusions may be drawn. Medical and psychological databases and cross-referencing were used to locate 913 potentially relevant articles. A table of 37 studies was constructed, consisting only of studies with prospective designs to ensure quality. Each study was reviewed for the population studied, the psychological predictor variables, and the outcome. The available literature indicated a clear link between psychological variables and neck and back pain. The prospective studies indicated that psychological variables were related to the onset of pain, and to acute, subacute, and chronic pain. Stress, distress, or anxiety as well as mood and emotions, cognitive functioning, and pain behavior all were found to be significant factors. Personality factors produced mixed results. Although the level of evidence was low, abuse also was found to be a potentially significant factor. Psychological factors play a significant role not only in chronic pain, but also in the etiology of acute pain, particularly in the transition to chronic problems. Specific types of psychological variables emerge and may be important in distinct developmental time frames, also implying that assessment and intervention need to reflect these variables. Still, psychological factors account for only a portion of the variance, thereby highlighting the multidimensional view. Because the methodologic quality of the studies varied considerably, future research should focus on improving quality and addressing new questions such as the mechanism, the developmental time factor, and the relevance that these risk factors have for intervention.
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                Author and article information

                Journal
                Reg Anesth Pain Med
                Reg Anesth Pain Med
                rapm
                rapm
                Regional Anesthesia and Pain Medicine
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                1098-7339
                1532-8651
                June 2020
                3 April 2020
                : 45
                : 6
                : 424-467
                Affiliations
                [1 ] departmentAnesthesiology, Pain Medicine Division , Johns Hopkins School of Medicine , Baltimore, Maryland, USA
                [2 ] departmentAnesthesiology , Imperial College Healthcare NHS Trust Haemodialysis Clinic Hayes Satellite Unit , Hayes, UK
                [3 ] departmentAnesthesia and Pain Management , University of Toronto and University Health Network—Toronto Western Hospital , Toronto, Ontario, Canada
                [4 ] departmentAnesthesiology , Rush University Medical Center , Chicago, Illinois, USA
                [5 ] Spine & Nerve Centers , Charleston, West Virginia, USA
                [6 ] departmentAnesthesiology , University of Cincinnati College of Medicine , Cincinnati, Ohio, USA
                [7 ] departmentAnesthesiology , Mayo Clinic , Rochester, Minnesota, USA
                [8 ] departmentAnesthesiology , Wake Forest School of Medicine , Winston-Salem, North Carolina, USA
                [9 ] departmentPhysical Medicine & Rehabilitation , Vanderbilt University School of Medicine , Nashville, Tennessee, USA
                [10 ] departmentAnesthesiology , Tripler Army Medical Center , Tripler Army Medical Center, Hawaii, USA
                [11 ] departmentDept of Anesthesiology , Seoul National University College of Medicine , Seoul, The Republic of Korea
                [12 ] departmentCenter for Pain Medicine , Summa Western Reserve Hospital , Cuyahoga Falls, Ohio, USA
                [13 ] departmentDept of Physical Medicine and Rehabilitation , VA Greater Los Angeles Healthcare System , Los Angeles, California, USA
                [14 ] Pain Diagnostics and Interventional Care , Sewickley, Pennsylvania, USA
                [15 ] Carolinas Pain Institute , Winston Salem, North Carolina, USA
                [16 ] Advanced Pain Therapy , Hattiesburg, Mississippi, USA
                [17 ] departmentDept.of Orthopaedic Surgery, Division of Physical Medicine & Rehabilitation , Stanford Medicine , Stanford, California, USA
                [18 ] departmentAnesthesiology, Critical Care and Multidisciplinary Pain Center , Ziekenhuis Oost-Limburg , Lanaken, Belgium
                [19 ] departmentAnesthesiology and Pain Medicine , Maastricht University Medical Center , Maastricht, The Netherlands
                [20 ] departmentAnesthesiology , Duke Medicine , Durham, North Carolina, USA
                [21 ] departmentAnesthesiology , UCSD Medical Center—Thornton Hospital , San Diego, California, USA
                [22 ] departmentNeurology , VA Healthcare Center District of Columbia , Washington, District of Columbia, USA
                Author notes
                [Correspondence to ] Dr Steven P Cohen, Anesthesiology, Pain Medicine Division, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; scohen40@ 123456jhmi.edu
                Author information
                http://orcid.org/0000-0001-5928-2127
                http://orcid.org/0000-0001-5645-6355
                http://orcid.org/0000-0002-5389-2036
                Article
                rapm-2019-101243
                10.1136/rapm-2019-101243
                7362874
                32245841
                18c232a0-2e42-4ca8-83ef-95a5c36017a5
                © American Society of Regional Anesthesia & Pain Medicine 2020. Re-use permitted under CC BY-NC. No commercial re-use. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, an indication of whether changes were made, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

                History
                : 21 December 2019
                : 07 February 2020
                : 11 February 2020
                Funding
                Funded by: MIRROR, Uniformed Services University of the Health Sciences, Dept. of Defense;
                Categories
                Special Article
                1506
                1507
                Custom metadata
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                interventional pain management,radiofrequency ablation,chronic pain: back pain,pain medicine,complications

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