Prospective study of 280 diabetic adults and 100 control show an association of limited joint mobility (LJM) with Dupuytren's contracture (DC) in 37 diabetic and no one of control case. In 80 diabetic with LJM, DC is found in 46.25 p. cent against 21 p. cent in 200 diabetic without LJM (p less than 0.00003). LJM and DC are significantly related to diabetic retinopathy and neuropathy. Their coexistence in diabetic patients, reported by other authors may be related to diffuse alteration of diabetic connective tissue.