Photo-polymeriable chitosan derivative prepared by Michael reaction of chitosan and polyethylene glycol diacrylate (PEGDA)

Abstract

N-Alkyled photo-polymeriable chitosan derivative (PEGDA-CS) was synthesized by Michael reaction of chitosan and polyethylene glycol diacrylate (PEGDA) under mild reaction conditions. The chemical structure and physical properties of PEGDA-CS were characterized by FT-IR, (1)H NMR, XRD and TG techniques. The degree of substitution (DS) of PEGDA-CS could be calculated from (1)H NMR. PEGDA-CS exhibited good solubility in distilled water. XRD analysis showed that PEGDA-CS was amorphous. TG results demonstrated that thermal stability of the derivate was lower than that of chitosan. Antimicrobial test showed that PEGDA-CS had the antimicrobial activity on Escherichia coli. It could photopolymerize under ultraviolet light with 2959 as initiator.