Acarbose and Idiopathic Reactive Hypoglycemia

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Abstract

Background/Aim: Therapy for idiopathic reactive hypoglycemia is ineffective and impractical. Acarbose, an α-glucosidase inhibitor, decreases the absorbed glucose load. This study was done to determine the efficacy of acarbose in this syndrome. Methods: Six patients with symptoms suggestive of postprandial hypoglycemia were chosen consecutively. Three-hour oral glucose tolerance tests using 75 g of glucose were done on each patient. The patients were then treated with acarbose with each meal. Results: All patients had symptomatic hypoglycemia during testing. After 4 weeks of acarbose therapy, all patients were asymptomatic on a regular diet. Conclusion: Acarbose is efficacious in the management of idiopathic reactive hypoglycemia.

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Most cited references 1

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Hypoglycemic disorders.

F John Service (1995)

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Author and article information

Journal

Journal ID (publisher-id): HRE

Journal ID (nlm-ta): Horm Res Paediatr

Journal ID (doi): 10.1159/issn.1663-2818

Title: Hormone Research in Paediatrics

Publisher: S. Karger AG

ISSN (Print): 1663-2818

ISSN (Electronic): 1663-2826

Publication date Subscription-year: 2003

Publication date (Print): 2003

Publication date (Electronic): 15 October 2003

Volume: 60

Issue: 4

Pages: 166-167

Affiliations

University of the West Indies, Nassau, Bahamas

Article

Publisher ID: 73227 Other ID: Horm Res 2003;60:166–167

DOI: 10.1159/000073227

PubMed ID: 14530603

SO-VID: 19078034-991e-4bb7-b750-52ecaae93992

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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date received : 24 March 2003

Date accepted : 27 May 2003

Page count

Tables: 1, References: 4, Pages: 2

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