β2-Glycoprotein I-Dependent Anti-Cardiolipin Antibodies Associated With Periodontitis in Patients With Systemic Lupus Erythematosus.

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Abstract

It was reported that patients with systemic lupus erythematosus (SLE) exhibited increased levels of anticardiolipin (anti-CL) antibodies, a class of antiphospholipid antibodies associated with thrombosis. β2-glycoprotein I (β2GPI) has been considered as the actual target antigen for anti-CL antibodies. This study investigates the association of periodontal infection with anti-CL antibodies in patients with SLE.

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Journal

Journal ID (iso-abbrev): J. Periodontol.

Title: Journal of periodontology

Publisher: American Academy of Periodontology (AAP)

ISSN (Electronic): 1943-3670

ISSN (Print): 0022-3492

Publication date (Electronic): Aug 2015

Volume: 86

Issue: 8

Affiliations

[1 ] Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.

[2 ] Department of Periodontology, National Taiwan University Hospital, Taipei, Taiwan.

[3 ] Department of Internal Medicine, Cathay General Hospital, Taipei, Taiwan.

[4 ] Graduate Institute of Immunology, College of Medicine, National Taiwan University.

[5 ] Department of Internal Medicine, National Taiwan University Hospital.

[6 ] Department of Integrated Dental Education, Division of Advanced Clinical Education, School of Dentistry, Health Sciences University of Hokkaido, Hokkaido, Japan.

[7 ] Department of Periodontology, Faculty of Dentistry, Khon Kaen University, Khon Kaen, Thailand.

Article

DOI: 10.1902/jop.2015.140664

PubMed ID: 25817824

SO-VID: 192eeb0d-1c42-4eb0-acd1-613e377acfbb

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Keywords: systemic lupus erythematosus,periodontitis,beta 2-glycoprotein I,anticardiolipin,Treponema denticola,Porphyromonas gingivalis,Antibodies

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Keywords: systemic lupus erythematosus, periodontitis, beta 2-glycoprotein I, anticardiolipin, Treponema denticola, Porphyromonas gingivalis, Antibodies

β2-Glycoprotein I-Dependent Anti-Cardiolipin Antibodies Associated With Periodontitis in Patients With Systemic Lupus Erythematosus.

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