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      A case of Brucella pyelonephritis: a rare case Translated title: Un caso de pielonefritis por Brucella: un caso raro

      case-report

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          Abstract

          Abstract Brucellosis is a zoonotic disease, seen globally, especially in developing countries and it can affect many organs. Urinary involvement of this disease is a very rare. Pyelonephritis, interstitial nephritis, glomerulonephritis, nephropathy are the reported urinary involvements. In this study, we aimed to report a case of Brucella pyelonephritis, who had complaints mimicking acute bacterial pyelonephritis, with a history of polycystic kidney disease and calculi in the left kidney.

          Translated abstract

          Resumen La brucelosis es una enfermedad zoonótica, vista globalmente, especialmente en países en vías de desarrollo y puede afectar muchos órganos. La afectación urinaria de esta enfermedad es muy rara. Pielonefritis, nefritis intersticial, glomerulonefritis y nefropatía son los compromisos urinarios reportados. En este estudio, nuestro objetivo fue informar un caso de pielonefritis por Brucella, que tenía síntomas que simulaban una pielonefritis bacteriana aguda, con antecedentes de poliquistosis renal y cálculos en el riñón izquierdo.

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          Most cited references15

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          Clinical manifestations, complications and treatment of brucellosis: a retrospective evaluation of 480 patients

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            Genitourinary brucellosis: results of a multicentric study.

            This study reviewed the clinical, laboratory, therapeutic and prognostic data on genitourinary involvement of brucellosis in this largest case series reported. This multicentre study pooled adult patients with genitourinary brucellar involvement from 34 centres treated between 2000 and 2013. Diagnosis of the disease was established by conventional methods. Overall 390 patients with genitourinary brucellosis (352 male, 90.2%) were pooled. In male patients, the most frequent involved site was the scrotal area (n=327, 83.8%), as epididymo-orchitis (n=204, 58%), orchitis (n=112, 31.8%) and epididymitis (n=11, 3.1%). In female patients, pyelonephritis (n=33/38, 86.8%) was significantly higher than in male patients (n=11/352, 3.1%; p<0.0001). The mean blood leukocyte count was 7530±3115/mm3. Routine laboratory analysis revealed mild to moderate increases for erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The mean treatment duration and length of hospital stay were significantly higher when there were additional brucellar foci (p<0.05). Surgical operations including orchiectomy and abscess drainage were performed in nine (2.3%) patients. Therapeutic failure was detected in six (1.5%), relapse occurred in four (1%), and persistent infertility related to brucellosis occurred in one patient. A localized scrotal infection in men or pyelonephritis in women in the absence of leucocytosis and with mild to moderate increases in inflammatory markers should signal the possibility of brucellar genitourinary disease.
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              Epidemiological assessment of 5598 brucellosis inpatients in Spain (1997–2015)

              Brucellosis remains one of the main zoonoses worldwide. Epidemiological data on human brucellosis in Spain are scarce. The objective of this study was to assess the epidemiological characteristics of inpatient brucellosis in Spain between 1997 and 2015. A retrospective longitudinal descriptive study was performed. Data were requested from the Health Information Institute of the Ministry of Health and Equality, which provided us with the Minimum Basic Data Set of patients admitted to the National Health System. We also obtained data published in the System of Obligatory Notifiable Diseases. A total of 5598 cases were registered. The period incidence rate was 0.67 (95% CI 0.65–0.68) cases per 100 000 person-years. We observed a progressive decrease in the number of cases and annual incidence rates. A total of 3187 cases (56.9%) came from urban areas. The group most at risk comprised men around the fifth decade of life. The average (± s.d. ) hospital stay was 12.6 days (±13.1). The overall lethality rate of the cohort was 1.5%. The number of inpatients diagnosed with brucellosis decreased exponentially. The group of patients with the highest risk of brucellosis in our study was males under 45 years of age and of urban origin. The lethality rate has reduced to minimum values. It is probable that hospital discharge records could be a good database for the epidemiological analysis of the hospital management of brucellosis and offer a better information collection system than the notifiable diseases system (EDO in Spanish).
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                Author and article information

                Journal
                ijm
                Iberoamerican Journal of Medicine
                Iberoam J Med
                Hospital San Pedro (Logroño, La Rioja, Spain )
                2695-5075
                2695-5075
                2022
                : 4
                : 2
                : 113-117
                Affiliations
                [3] Bitlis orgnameBitlis State Hospital orgdiv1Department of Emergency Medicine Turquía
                [1] Canakkale orgnameÇanakkale Onsekiz Mart University Faculty of Medicine orgdiv1Department of Infectious Disease Turquía
                [2] Bitlis orgnameBitlis State Hospital orgdiv1Department of Indectious Disease and Clinical Microbiology Turquía
                Article
                S2695-50752022000200006 S2695-5075(22)00400200006
                10.53986/ibjm.2022.0012
                194777b6-bab5-4391-9e16-8177dd4c625a

                This work is licensed under a Creative Commons Attribution 4.0 International License.

                History
                : 14 February 2022
                : 11 December 2021
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 15, Pages: 5
                Product

                SciELO Spain

                Categories
                Case Report

                Brucella,Brucellosis,Pyelonephtiyis,Brucelosis,Pielonefritis

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