17
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Validation of a method to monitor the occurrence of 20 relevant pharmaceuticals and personal care products in 167 bottled waters.

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Research on emerging substances in drinking water presents major interest and the possibility of trace contamination has seen increasing concern from the scientific community and the public authorities. More particularly, residues of pharmaceuticals and personal care products (PPCPs) in bottled water are a very important issue due to societal concerns and potential media impact. In this context, it has become necessary to carry out reliable monitoring. This requires measurements of high quality with demonstration of accuracy and well-defined uncertainty. In this study, 20 pharmaceutical compounds were targeted for the first time in 167 bottled waters from France and other European countries. An isotope dilution-solid phase extraction-liquid chromatography mass spectrometry method, together with stringent quality control and quality assurance protocols, was developed and validated according to French mandatory standards. Recoveries between 87% and 112% were obtained with coefficient of variation below 20%. Operational limits of quantification (LOQ) were comprised between 5 and 30ngL(-1). Expanded uncertainties (k=2) ranged between 16% and 43% and were below 35% for half of the compounds. The survey showed only four positive quantifications, thereby highlighting the rarity of contamination.

          Related collections

          Author and article information

          Journal
          Sci. Total Environ.
          The Science of the total environment
          Elsevier BV
          1879-1026
          0048-9697
          Jun 01 2017
          : 587-588
          Affiliations
          [1 ] Laboratoire National de métrologie et d'Essais (LNE), 1 rue Gaston Boissier, 75724 Paris, France,. Electronic address: sophie.lardy-fontan@lne.fr.
          [2 ] Laboratoire National de métrologie et d'Essais (LNE), 1 rue Gaston Boissier, 75724 Paris, France.
          [3 ] ANSES Nancy Laboratory for Hydrology, Water Chemistry Department, 40 Rue Lionnois, 54 000 Nancy, France.
          Article
          S0048-9697(17)30315-7
          10.1016/j.scitotenv.2017.02.074
          28242224
          1953f446-1c28-463e-a0dc-c0d244d6ada9
          History

          Bottled waters,Personal care products,Pharmaceuticals,QA/QC,Quality of measurements

          Comments

          Comment on this article