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      Inferior alveolar nerve dysfunction in mandibular fractures: a prospective cohort study

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          Abstract

          Objectives

          To assess the prevalence and recovery of inferior alveolar nerve dysfunction (IAND) in mandibular fractures.

          Materials and Methods

          This was a prospective cohort study. Clinical neurosensory testing was done preoperatively and the IAND was categorized as mild, moderate or severe. Postoperatively, neurosensory testing was repeated at 1 day, 1 week, 1 month, 3 months and every 3 months thereafter.

          Results

          A total of 257 patients with 420 fractures were included in the study with a mean age of 31.7 years. Body fractures (95.9%) had the highest incidence of IAND, followed by the angle fractures (90.1%) and symphysis fractures (27.6%). The condyle and coronoid fractures did not have any IAND and hence were excluded from further study. After eliminating those cases, 232 patients remained in the study with 293 fractures. The overall prevalence of IAND in fractures occurring distal to the mandibular foramen was 56.3%. The changes until 1 week were minimal. From 1 month to 6 months, there was a significant reduction in the severity of IAND. A significant number of cases (60.0%) were lost to follow-up between 6 and 9 months. At 6 months, 23.9% of cases still had some form of IAND and 95.0% of the symphysis, 59.0% of the angle and 34.8% of the body fractures with IAND had become normal.

          Conclusion

          This study documents the reduction in the degree of severity of IAND in the first six months and provides the basis for future studies with longer periods of follow-up.

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          Most cited references20

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          Ten years of mandibular fractures: an analysis of 2,137 cases.

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            Sensory testing of inferior alveolar nerve injuries: a review of methods used in prospective studies.

            The inferior alveolar nerve (IAN) can be injured during trauma or surgery. So far there is no consensus for evaluating IAN injury. This study aimed to identify a testing method suitable for daily clinical practice which allows us to identify nerve injury, grade its severity, and monitor its recovery. Covering a 20-year period, prospective studies on sensory changes after mandibular procedures were reviewed regarding sensory testing methods; 75 studies on third molar removal, osteotomy, fracture, and implants were included. These studies reported varying incidences. In third molar removal and implant studies, a limited number of sensory tests were used, whereas in osteotomy and fracture studies more detailed testing was performed, using reproducible tests like light touch test with Semmes-Weinstein monofilaments and 2-point discrimination. Sensory function was not uniformly tested and presented, making a comparison of data impossible and highlighting the need for uniform testing methodology. Based on the results of this review, the light touch test with Semmes-Weinstein monofilaments for grading is recommended, using a grid and control site describing unilateral or bilateral nerve injury. Additionally, a visual analog scale-based questionnaire should be used to evaluate subjective sensibility. Using this method to test IAN injuries will allow comparison of future studies and provide valuable insight in the severity and prognosis of IAN injuries.
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              Prospective study on post-traumatic and postoperative sensory disturbances of the inferior alveolar nerve and infraorbital nerve in mandibular and midfacial fractures.

              In a prospective study (January 1999 to December 1997), 34 patients with 26 mandibular and 20 midfacial fractures were investigated. All the fractures were managed by osteosynthesis. To evaluate the incidence and duration of recovery of post-traumatic and postoperative sensory disturbances, the following tests were carried out: sharp/blunt testing, and the two-point discrimination test as conventional clinical examination methods, and electromyographic recording of the masseter reflex to calibrate the clinical findings. To establish the sensory status of the inferior alveolar and the infraorbital nerves in the region of the fracture, and on the intact and control sides, the tests were performed pre-operatively and postoperatively on the seventh day, after 4 weeks and after 3, 6 and 12 months. The incidence of post-traumatic sensory disturbance was 46% for mandibular fractures and 65% for fractures to the midface (sharp/blunt test, two-point discrimination test). The rate of postoperative sensory disturbance in surgical treatment of mandibular fracture involving the region of the intra bony course of the inferior alveolar nerve, including the post-traumatic sensory disturbance, was 76.9%, and 55% following surgical treatment of midfacial fractures. The incidence of persistent sensory disturbances following surgical treatment was 7.7% in the case of mandibular fractures, and 15% in the case of midfacial fractures (sharp/blunt test, two-point discrimination test, masseter reflex). Recovery of neurological function is delayed in the presence of a displaced fracture (> 1 mm) as compared with non-displaced fractures. For the postoperative calibration of sensory disturbances, electromyographic recording of the masseter reflex from the fourth postoperative week onwards has proved useful.
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                Author and article information

                Journal
                J Korean Assoc Oral Maxillofac Surg
                J Korean Assoc Oral Maxillofac Surg
                Journal of the Korean Association of Oral and Maxillofacial Surgeons
                The Korean Association of Oral and Maxillofacial Surgeons
                2234-7550
                2234-5930
                30 June 2021
                30 June 2021
                30 June 2021
                : 47
                : 3
                : 183-189
                Affiliations
                [1 ]Department of Oral and Maxillofacial Surgery, JSS Dental College, JSS Academy of Higher Education and Research, Mysore, India
                [2 ]Department of Oral and Maxillofacial Surgery, Rajarajeshwari Dental College, Bangalore, India
                Author notes
                Chandan S N, Department of Oral and Maxillofacial Surgery, JSS Dental College, JSS Academy of Higher Education and Research, SS Nagar, Mysore 570015, India, TEL: +91-9448307430, E-mail: dr.chandansn@ 123456jssuni.edu.in , ORCID: https://orcid.org/0000-0001-6011-2811
                Author information
                https://orcid.org/0000-0001-6011-2811
                https://orcid.org/0000-0002-8163-3904
                https://orcid.org/0000-0002-4665-2093
                https://orcid.org/0000-0001-7986-1820
                Article
                jkaoms-47-3-183
                10.5125/jkaoms.2021.47.3.183
                8249188
                34187958
                195ab670-769c-4ebc-bacd-f8b557647384
                Copyright © 2021 The Korean Association of Oral and Maxillofacial Surgeons. All rights reserved.

                This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( http://creativecommons.org/licenses/by-nc/4.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 17 December 2020
                : 23 February 2021
                : 4 March 2021
                Categories
                Original Article

                mandibular fractures,sensation disorders,inferior alveolar nerve,prevalence

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