Comparative Observations of the Impairment of Autonomic Responses in Chronic Chagas' Heart Disease and in African Myocardiopathies

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Abstract

Failure to increase heart rate following administration of atropine and greatly-reduced reflex changes in cardiac rate during acutely-induced alterations in blood pressure in chronic chagasic cardiac patients are believed to be a functional disorder related to degeneration of the neuronal supply to the sino-atrial region of the heart. The fact that patients with myocardiopathies of other etiologies respond differently than the Chagas'' cases strengthens the evidence for the specific loss of autonomic control in the latter.

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Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1970

Publication date (Print): 1970

Publication date (Electronic): 29 October 2008

Volume: 55

Issue: 6

Pages: 321-332

Affiliations

School of Medicine of Ribeirão Prêto, University of São Paulo, São Paulo, University of Cape Town, Cape Town, and Makerere University College, Kampala

Article

Publisher ID: 169296 Other ID: Cardiology 1970;55:321–332

DOI: 10.1159/000169296

SO-VID: 196950a2-5dcc-4e49-8dcf-5167cd7adaa7

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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

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Pages: 12

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Cited by 1

Functional alterations of the autonomic nervous system in Chagas' heart disease
Authors: Dalmo Amorim, José Marin Neto

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