M. Ghannad: Role: Writing – original draftRole: Writing – review & editing
M. Dennehy: Role: ConceptualizationRole: Formal analysisRole: SupervisionRole: Writing – review
& editing
C. la Porte: Role: MethodologyRole: Writing – review & editing
I. Seguin: Role: ConceptualizationRole: InvestigationRole: Project administrationRole: ResourcesRole:
Supervision
D. Tardiff: Role: InvestigationRole: Project administration
R. Mallick: Role: Formal analysisRole: Investigation
E. Sabri: Role: Formal analysis
G. Zhang: Role: Data curationRole: Formal analysisRole: InvestigationRole: Writing – review
& editing
S. Kanji: Role: Writing – review & editing
D. W. Cameron:
ORCID: http://orcid.org/0000-0002-0090-3539
Role: ConceptualizationRole: Formal analysisRole: Funding acquisitionRole: InvestigationRole:
MethodologyRole: Project administrationRole: SupervisionRole: Writing – original draftRole:
Writing – review & editing
Giuseppe Vittorio De Socio: Role: Editor
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
24
October
2019
Publication date Collection: 2019
Volume: 14
Issue: 10
Electronic Location Identifier: e0223969
Affiliations
[1
]
Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
[2
]
Clinical Investigation Unit, The Ottawa Hospital, Ottawa, Ontario, Canada
[3
]
Ottawa Methods Centre, Clinical Epidemiology Program, Ottawa Hospital Research Institute,
Ottawa, Ontario, Canada
[4
]
The Ottawa Hospital, Department of Pharmacy, Ottawa, Ontario, Canada
[5
]
Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario,
Canada
[6
]
Division of Infectious Diseases, Department of Medicine, University of Ottawa at The
Ottawa Hospital, Ottawa, Ontario, Canada
Azienda Ospedaliera Universitaria di Perugia, ITALY
Author notes
Competing Interests: ViiV Healthcare, a Pfizer affiliate, funded this study. CLP began working for Janssen
after the conclusion of the study. Janssen had no role in this study and did not contribute
any funding. There are no patents, products in development or marketed products to
declare. This does not alter our adherence to PLOS ONE policies on sharing data and
materials.
[¤]
Current address: The Janssen Pharmaceutical Companies of Johnson & Johnson, Breda,
Netherlands
Author information
Article
Publisher ID:
PONE-D-19-22400
DOI: 10.1371/journal.pone.0223969
PMC ID: 6812819
PubMed ID: 31647836
SO-VID: 19c634c8-6d6d-4caf-a30a-4e922a208c01
Copyright © © 2019 Ghannad et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
This study was funded by ViiV Healthcare, a Pfizer affiliate. The Department of Medicine,
University of Ottawa at The Ottawa Hospital provided support to DWC. ViiV Healthcare
and the University of Ottawa had no role in study design, data collection and analysis,
decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Pharmacokinetics
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Pharmacokinetics
Subject:
Drug Metabolism
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Immunodeficiency Viruses
Subject:
HIV
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Immunodeficiency Viruses
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral Pathogens
Subject:
Immunodeficiency Viruses
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Immunodeficiency Viruses
Subject:
HIV
Subject:
Biology and life sciences
Subject:
Organisms
Subject:
Viruses
Subject:
RNA viruses
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Microbiology
Subject:
Medical Microbiology
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
HIV
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Pathogens
Subject:
Microbial Pathogens
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
HIV
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Viruses
Subject:
Viral Pathogens
Subject:
Retroviruses
Subject:
Lentivirus
Subject:
HIV
Subject:
Medicine and Health Sciences
Subject:
Pharmaceutics
Subject:
Drug Therapy
Subject:
Medicine and Health Sciences
Subject:
Pharmacology
Subject:
Drug Interactions
Subject:
Drug-Drug Interactions
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Signs and Symptoms
Subject:
Pain
Subject:
Myalgia
Subject:
Medicine and Health Sciences
Subject:
Pathology and Laboratory Medicine
Subject:
Signs and Symptoms
Subject:
Pain
Subject:
Myalgia
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Enzymology
Subject:
Enzyme Chemistry
Subject:
Enzyme Metabolism
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Enzymology
Subject:
Enzymes
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Enzymes
