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      The ordinary work environment increases symptoms from eyes and airways in mild steel welders

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          Abstract

          Purpose

          We aimed to follow diary-registered symptoms from eyes and airways in mild steel welders and relate them to different exposure measures. Furthermore, we would clarify the influence of possible effect modifiers.

          Methods

          Non-smoking welders with ( N = 74) and without ( N = 32) work-related symptoms the last month were enroled. Symptoms and work tasks each day for three two-week periods during 1 year were obtained. Respirable dust (RD) was measured 1 day each period for each worker. The personal daily exposure was assessed as: (1) days at work, (2) welding time and (3) estimates of RD from welding and grinding, calculated from diary entries and measurements.

          Results

          Only 9.2 % of the particle measurements exceed the Swedish occupational exposure limit (OEL; 5 mg/m 3). Days at work increased the risk of symptoms studied: eyes: 1.79 (1.46–2.19), nasal: 2.16 (1.81–2.58), dry cough: 1.50 (1.23–1.82) and wheezing and/or dyspnoea: 1.27 (1.03–1.56; odds ratio, 95 % confidence interval). No clear dose–response relationships were found for the other exposure estimates. Eye symptoms increased by number of years welding. Nasal symptoms and dry cough increased having forced expiratory volume in first second below median at baseline. Wheezing and/or dyspnoea increased in winter, by number of years welding, having a negative standard skin-prick test and having a vital capacity above median at baseline.

          Conclusion

          The current Swedish OEL may not protect welders against eye and airway symptoms. The results add to the evidence that welders should be offered regular medical surveillance from early in the career.

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          Most cited references28

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          Epidemiology Standardization Project (American Thoracic Society).

          B G Ferris (1978)
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            Health effects of welding.

            Many of the epidemiology studies performed are difficult to compare because of differences in worker populations, industrial settings, welding techniques, duration of exposure, and other occupational exposures besides welding fumes. Some studies were conducted in carefully controlled work environments, others during actual workplace conditions, and some in laboratories. Epidemiology studies have shown that a large number of welders experience some type of respiratory illness. Respiratory effects seen in full-time welders have included bronchitis, airway irritation, lung function changes, and a possible increase in the incidence of lung cancer. Pulmonary infections are increased in terms of severity, duration, and frequency among welders. Although epidemiological studies have demonstrated an increase in pulmonary illness after exposure to welding fumes, little information of the causality, dose-response, and possible underlying mechanisms regarding the inhalation of welding fumes exists. Even less information is available about the neurological, reproductive, and dermal effects after welding fume exposure. Moreover, carcinogenicity and short-term and long-term toxicology studies of welding fumes in animals are lacing or incomplete. Therefore, an understanding of possible adverse health effects of exposure to welding fumes is essential to risk assessment and the development of prevention strategies and will impact a large population of workers.
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              Occupational exposure to welding fume among welders: alterations of manganese, iron, zinc, copper, and lead in body fluids and the oxidative stress status.

              Welders in this study were selected from a vehicle manufacturer; control subjects were from a nearby food factory. Airborne manganese levels in the breathing zones of welders and controls were 1.45 +/- SD1.08 mg/m and 0.11 +/- 0.07 microg/m, respectively. Serum levels of manganese and iron in welders were 4.3-fold and 1.9-fold, respectively, higher than those of controls. Blood lead concentrations in welders increased 2.5-fold, whereas serum zinc levels decreased 1.2-fold, in comparison with controls. Linear regression revealed the lack of associations between blood levels of five metals and welder's age. Furthermore, welders had erythrocytic superoxide dismutase activity and serum malondialdehyde levels 24% less and 78% higher, respectively, than those of controls. These findings suggest that occupational exposure to welding fumes among welders disturbs the homeostasis of trace elements in systemic circulation and induces oxidative stress.
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                Author and article information

                Contributors
                +4646173178 , jorn.nielsen@med.lu.se
                Journal
                Int Arch Occup Environ Health
                Int Arch Occup Environ Health
                International Archives of Occupational and Environmental Health
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                0340-0131
                1432-1246
                6 March 2015
                6 March 2015
                2015
                : 88
                : 8
                : 1131-1140
                Affiliations
                [ ]Division of Occupational and Environmental Medicine, Lund University Hospital, 22185 Lund, Sweden
                [ ]Medical Statistics and Epidemiology Unit, R&D Centre Skåne, Skåne University Hospital, Lund, Sweden
                Article
                1041
                10.1007/s00420-015-1041-2
                4608979
                25744592
                19f4f8ed-2c9f-476c-ae1b-63112c0082ca
                © The Author(s) 2015

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.

                History
                : 9 July 2014
                : 24 February 2015
                Categories
                Original Article
                Custom metadata
                © Springer-Verlag Berlin Heidelberg 2015

                Occupational & Environmental medicine
                work-related symptoms,diary study,risk factors,medical surveillance

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