objective: The purpose of this study is to evaluate the effect of an educational program on pressure ulcer prevention intervention among nurses in intensive care units at a public hospital in Pakistan. design: It is a Quasi experimental study. Participants: 144 staff nurses with different educational backgrounds working more than 6 month in an intensive care units were participants. methods: They were evaluated pre-test. Workshops, lectures and hands on practice related to pressure ulcer prevention intervention were conducted. After these interventions post-tests were taken results: There was a major difference between the mean knowledge score about the pressure ulcer preventive measures among nurses before (5.73±1.488) and after (12.01±.908) education sessions. P value is 0.000 which was less than .001 shows a significant difference in mean knowledge score before and after the education. conclusion: Knowledge base practices improved the quality of life and care. In the current study, post-test knowledge of nurses after a seminar, lecture and literature which given by the researcher, show improvement and most of the nurses get high marks in post-test session.