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      Clinical Applications of Myocardial Perfusion Assessments Made with Oxygen-15 Water and Positron Emission Tomography

      Cardiology

      S. Karger AG

      Myocardial blood flow, Radionuclides, Tracers

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          Abstract

          Positron emission tomography is an intrinsically quantitative tool which permits the quantitative assessment (i.e., in ml/g/min) of regional myocardial perfusion. Oxygen-15-labeled water is the only positron-emitting flow tracer which is freely diffusible within the myocardium. It has been used extensively to define normal myocardial perfusion physiology, as well as to delineate the effects of numerous cardiac diseases on myocardial perfusion and to assess the efficacy of therapeutic interventions. This brief review summarizes the major observations that have been made in humans using oxygen-15 water and positron emission tomography for quantitative estimation of regional myocardial perfusion.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1997
          1997
          19 November 2008
          : 88
          : 1
          : 71-79
          Affiliations
          Cardiovascular Division, Washington University School of Medicine, St. Louis, Mo., USA
          Article
          177313 Cardiology 1997;88:71–79
          10.1159/000177313
          8960629
          © 1997 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 9
          Categories
          Myocardial Blood Flow Symposium

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