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      Estimating the rate of evolution of the rate of molecular evolution.

      1 , ,

      Molecular biology and evolution

      Oxford University Press (OUP)

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          Abstract

          A simple model for the evolution of the rate of molecular evolution is presented. With a Bayesian approach, this model can serve as the basis for estimating dates of important evolutionary events even in the absence of the assumption of constant rates among evolutionary lineages. The method can be used in conjunction with any of the widely used models for nucleotide substitution or amino acid replacement. It is illustrated by analyzing a data set of rbcL protein sequences.

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          Author and article information

          Journal
          Mol Biol Evol
          Molecular biology and evolution
          Oxford University Press (OUP)
          0737-4038
          0737-4038
          Dec 1998
          : 15
          : 12
          Affiliations
          [1 ] Statistics Department, North Carolina State University, Raleigh 27695-8203, USA. thorne@statgen.ncsu.edu
          Article
          10.1093/oxfordjournals.molbev.a025892
          9866200
          1a9f4b37-a306-4f7c-9a3d-05ba863a8aa8

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