- Record: found
- Abstract: not found
- Article: not found
The Sensitive Period for Strabismic Amblyopia in Humans
March 1993
March 1993
There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.
Abstract
In order to assess the sensitive period for strabismic amblyopia, the period of susceptibility
to monocular occlusion was investigated in 407 children who ranged in age from 21
months to 12 years.
Patients were treated between 1975 and 1990 by occlusion of the best eye. The efficiency
of the treatment was measured as the ratio of reduction of the amblyopia at the end
of the occlusion.
The efficiency of the occlusion is shown to depend on the age of the onset of the
treatment: recovery of acuity of the amblyopic eye was maximum when the occlusion
was initiated before 3 years of age, decreased as a function of age and was about
null by the time the patient was 12 years of age.
This is assumed to be an indication of the sensitive period for strabismic amblyopia
in humans. The results are discussed on the basis of the neurophysiological mechanisms
of amblyopia established in animals.