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      Caffeine and sports performance.

      Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme
      methods, Doping in Sports, Humans, Athletic Performance, Central Nervous System Stimulants, drug effects, statistics & numerical data, Physical Endurance, pharmacology, prevention & control, physiology, Cross-Over Studies, Caffeine, Exercise Tolerance, Male, Female

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          Abstract

          Athletes are among the groups of people who are interested in the effects of caffeine on endurance and exercise capacity. Although many studies have investigated the effect of caffeine ingestion on exercise, not all are suited to draw conclusions regarding caffeine and sports performance. Characteristics of studies that can better explore the issues of athletes include the use of well-trained subjects, conditions that reflect actual practices in sport, and exercise protocols that simulate real-life events. There is a scarcity of field-based studies and investigations involving elite performers. Researchers are encouraged to use statistical analyses that consider the magnitude of changes, and to establish whether these are meaningful to the outcome of sport. The available literature that follows such guidelines suggests that performance benefits can be seen with moderate amounts (~3 mg.kg-1 body mass) of caffeine. Furthermore, these benefits are likely to occur across a range of sports, including endurance events, stop-and-go events (e.g., team and racquet sports), and sports involving sustained high-intensity activity lasting from 1-60 min (e.g., swimming, rowing, and middle and distance running races). The direct effects on single events involving strength and power, such as lifts, throws, and sprints, are unclear. Further studies are needed to better elucidate the range of protocols (timing and amount of doses) that produce benefits and the range of sports to which these may apply. Individual responses, the politics of sport, and the effects of caffeine on other goals, such as sleep, hydration, and refuelling, also need to be considered.

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          Caffeine and Exercise

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            Exercise endurance 1, 3, and 6 h after caffeine ingestion in caffeine users and nonusers.

            The purpose of the present study was to examine the duration of caffeine's ergogenic effect and whether it differs between users and nonusers of the drug. Twenty-one subjects (13 caffeine users and 8 nonusers) completed six randomized exercise rides to exhaustion at 80% of maximal oxygen consumption after ingesting either a placebo or 5 mg/kg of caffeine. Exercise to exhaustion was completed once per week at either 1, 3, or 6 h after placebo or drug ingestion. Exercise time to exhaustion differed between users and nonusers with the ergogenic effect being greater and lasting longer in nonusers. For the nonusers, exercise times 1, 3, and 6 h after caffeine ingestion were 32.7 +/- 8.4, 32.1 +/- 8.6, and 31.7 +/- 12.0 min, respectively, and these values were each significantly greater than the corresponding placebo values of 24.2 +/- 6.4, 25.8 +/- 9.0, and 23.2 +/- 7.1 min. For caffeine users, exercise times 1, 3, and 6 h after caffeine ingestion were 27.4 +/- 7.2, 28.1 +/- 7.8, and 24.5 +/- 7.6 min, respectively. Only exercise times 1 and 3 h after drug ingestion were significantly greater than the respective placebo trials of 23.3 +/- 6.5, 23.2 +/- 7.1, and 23.5 +/- 5.7 min. In conclusion, both the duration and magnitude of the ergogenic effect that followed a 5 mg/kg dose of caffeine were greater in the nonusers compared with the users.
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              Effect of caffeine ingestion on one-repetition maximum muscular strength.

              Multiple studies corroborate the ergogenic properties of caffeine (CAF) for endurance performance, yet fewer investigations document the efficacy of acute caffeine intake for intense, short-term exercise. The aim of the study was to determine the ergogenic potential of caffeine during testing of muscular strength and endurance. Twenty-two resistance-trained men ingested CAF (6 mg/kg) or placebo (PL) 1 h pre-exercise in a randomized, double-blind crossover design. They refrained from caffeine intake and strenuous exercise 48 and 24 h, respectively, pre-visit. Initially, resting heart rate and blood pressure were obtained followed by one-repetition maximum (1-RM) testing on the barbell bench press and leg press. Upon determination of 1-RM, participants completed repetitions to failure at 60%1-RM. Heart rate, blood pressure, and rating of perceived exertion (RPE) were measured after the final repetition. Compared to PL, there was no effect (P > 0.05) of caffeine on muscular strength, as 1-RM bench press (116.4 +/- 23.6 kg vs. 114.9 +/- 22.8 kg) and leg press (410.6 +/- 92.4 kg vs. 394.8 +/- 95.4 kg) were similar. Total weight lifted during the 60% 1-RM trial was 11 and 12% higher for the bench press and leg press with caffeine compared to placebo, yet did not reach significance. RPE was similar at the end of resistance exercise with CAF vs. PL. Acute caffeine intake does not significantly alter muscular strength or endurance during intense bench press or leg press exercise, yet the practical importance of the increased muscular endurance remains to be explored.
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